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Reviews of Physiology, Biochemistry and Pharmacology 160

E-BookPDF1 - PDF WatermarkE-Book
125 Seiten
Englisch
Springer Berlin Heidelbergerschienen am15.05.20082008
Reviews of Physiology, Biochemistry and Pharmacology
Volume 160 2008

V. di Marzo: Endocannabinoids: Synthesis and Degradation
R. Rivera and J. Chun: Biological Effects of Lysophospholipids
S. J. O'Meara, K. Rodgers, and C. Godson: Lipoxins: Update and Impact of Endogenous Pro-Resolution Lipid Mediators
R.K.P. Benninger, M. Hao, and D. Piston: Multi-photon Excitation Imaging of Dynamic Processes in Living Cells and Tissues
G. Schmitz and M. Grandl: Lipid Homeostasis in Macrophages - Implications for Atherosclerosis
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E-BookPDF1 - PDF WatermarkE-Book
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Produkt

KlappentextReviews of Physiology, Biochemistry and Pharmacology
Volume 160 2008

V. di Marzo: Endocannabinoids: Synthesis and Degradation
R. Rivera and J. Chun: Biological Effects of Lysophospholipids
S. J. O'Meara, K. Rodgers, and C. Godson: Lipoxins: Update and Impact of Endogenous Pro-Resolution Lipid Mediators
R.K.P. Benninger, M. Hao, and D. Piston: Multi-photon Excitation Imaging of Dynamic Processes in Living Cells and Tissues
G. Schmitz and M. Grandl: Lipid Homeostasis in Macrophages - Implications for Atherosclerosis
Details
Weitere ISBN/GTIN9783540776048
ProduktartE-Book
EinbandartE-Book
FormatPDF
Format Hinweis1 - PDF Watermark
FormatE107
Erscheinungsjahr2008
Erscheinungsdatum15.05.2008
Auflage2008
Reihen-Nr.160
Seiten125 Seiten
SpracheEnglisch
IllustrationenIV, 125 p. 20 illus., 10 illus. in color.
Artikel-Nr.1430246
Rubriken
Genre9200

Inhalt/Kritik

Inhaltsverzeichnis
1;Endocannabinoids: synthesis and degradation;5
1.1;Endocannabinoids;5
1.2;Commonalities between anandamide and 2-AG anabolic and catabolic reactions;6
1.3;Anandamide biosynthesis: one or more pathways?;8
1.4;2-AG biosynthesis: perhaps less complicated than originally thought;10
1.5;Biosynthesis of NADA and other endocannabinoids: more questions than answers;12
1.6;The endocannabinoid membrane transporter: an unknown between release and re- uptake;12
1.7;Fatty acid amide hydrolase: AEA degradation and beyond;14
1.8;2-AG degradation: redundancy again;15
1.9;Endocannabinoid oxidation and its possible role;17
1.10;Regulation of endocannabinoid levels: what is the target, biosynthesis or degradation?;18
1.11;Conclusions: new therapeutic drugs from studies of endocannabinoid synthesis and degradation;20
1.12;References;21
2;Biological effects of lysophospholipids;29
2.1;Introduction;29
2.2;S1P receptors;32
2.3;LPA receptors;39
2.4;Conclusions and future prospects;44
2.5;References;45
3;Lipoxins: update and impact of endogenous pro- resolution lipid mediators;51
3.1;Introduction;51
3.2;Lipoxin biosynthesis and metabolism;52
3.3;Resolvins;53
3.4;Metabolism;53
3.5;Bioactions of lipoxins;54
3.6;Mechanisms of lipoxin action: receptors and signalling pathways;55
3.7;Transcription factors involved in lipoxin A4 signalling;62
3.8;Lipoxins in inflammation and disease;63
3.9;Intestinal inflammation;64
3.10;Respiratory disease;65
3.11;Glomerulonephritis and renal diseases;65
3.12;Angiogenesis;66
3.13;Tuberculosis;67
3.14;Ocular wound healing;67
3.15;Conclusions;68
3.16;References;68
4;Multi-photon excitation imaging of dynamic processes in living cells and tissues;75
4.1;Introduction;76
4.2;Two-photon absorption and the two-photon microscope;77
4.3;Applications of two-photon microscopy;79
4.4;The future;91
4.5;References;93
5;Lipid homeostasis in macrophages - Implications for atherosclerosis;97
5.1;Macrophages and atherosclerosis;99
5.2;Differential expression of the monocyte innate immunity receptor complex defining monocyte subpopulations;101
5.3;Receptor entry pathways of modified LDL;103
5.4;Specific characteristics of E-LDL and Ox-LDL;105
5.5;Abnormalities of cholesterol trafficking;108
5.6;Cellular cholesterol metabolism and lipid storage;109
5.7;Cholesterol efflux from macrophages to prevent foam cell formation;111
5.8;ABCA1-interacting proteins and lipid membrane microdomains;113
5.9;Regulation of cellular cholesterol levels through transcription factors;115
5.10;Niacin, statins, CETP inhibitors, apoA-I mimetics, and ezetimibe as pharmacological modulators of lipid homeostasis;117
5.11;Conclusion;118
5.12;Glossary;119
5.13;References;120
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