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Cardiomyocytes - Active Players in Cardiac Disease

E-BookPDF1 - PDF WatermarkE-Book
278 Seiten
Englisch
Springer International Publishingerschienen am28.06.20161st ed. 2016
This book summarizes our current understanding about the biology and patho-biology of cardiomyocytes and depicts common techniques for the study of these cells. The book is divided into two parts; the first part provides insight into role and function of cardiomyocytes under normal conditions and describes embryogenesis and differentiation, in the second part the role of cardiomyocytes in aging and disease is discussed and cellular responses under stress conditions illustrated. Cardiomyocytes represent the main mass of the heart, and cellular malfunction directly modifies heart function leading to subsequent heart failure. As such, cardiomyocytes are causative involved in the main reasons of heart failure, such as post-infarct remodeling, hypertensive heart disease, idiopathic heart failure, and interactions with other co-morbidities such as diabetes. On the other hand, cardiomyocytes are necessarily target of therapy. Therefore, a precise understanding of cardiomyocytes biology is a pre-requisite for proper disease treatment and evidence based medicine.
The book is written for cell biologists, pharmacologists and biomedical researchers specialized in cardiac and vascular biology.

 


Prof. Dr. Klaus-Dieter Schlüter Institute of Physiology JLU Giessen Giessen, Germanymehr
Verfügbare Formate
BuchGebunden
EUR160,49
E-BookPDF1 - PDF WatermarkE-Book
EUR149,79

Produkt

KlappentextThis book summarizes our current understanding about the biology and patho-biology of cardiomyocytes and depicts common techniques for the study of these cells. The book is divided into two parts; the first part provides insight into role and function of cardiomyocytes under normal conditions and describes embryogenesis and differentiation, in the second part the role of cardiomyocytes in aging and disease is discussed and cellular responses under stress conditions illustrated. Cardiomyocytes represent the main mass of the heart, and cellular malfunction directly modifies heart function leading to subsequent heart failure. As such, cardiomyocytes are causative involved in the main reasons of heart failure, such as post-infarct remodeling, hypertensive heart disease, idiopathic heart failure, and interactions with other co-morbidities such as diabetes. On the other hand, cardiomyocytes are necessarily target of therapy. Therefore, a precise understanding of cardiomyocytes biology is a pre-requisite for proper disease treatment and evidence based medicine.
The book is written for cell biologists, pharmacologists and biomedical researchers specialized in cardiac and vascular biology.

 


Prof. Dr. Klaus-Dieter Schlüter Institute of Physiology JLU Giessen Giessen, Germany
Details
Weitere ISBN/GTIN9783319312514
ProduktartE-Book
EinbandartE-Book
FormatPDF
Format Hinweis1 - PDF Watermark
FormatE107
Erscheinungsjahr2016
Erscheinungsdatum28.06.2016
Auflage1st ed. 2016
Seiten278 Seiten
SpracheEnglisch
IllustrationenXV, 278 p. 40 illus., 13 illus. in color.
Artikel-Nr.1961401
Rubriken
Genre9200

Inhalt/Kritik

Inhaltsverzeichnis
Cardiomyocytes: Function and Regeneration.- 1.Ways to study the biology of cardiomyocytes.-2.Cardiomyocytes: Function and Regeneration.- 3.Excitation-contraction couplingof cardiomyocytes.- 4.Cardiac metabolism and energetic control.- 5.Endogenousmechanisms for regulating myocardial contractility.- Cardiomyocytes in ageing,disease, and protection.- 6.Growth regulation of cardiomyocytes: Control ofcell size and its role in cardiac hypertrophy.- 7.Protein Degradation inCardiomyocytes - Target Proteins and clinical consequences.- 8.Ischemia andReperfusion.- 9.Mechanisms of cardiac cell death.- 10.Oxidative stress andnitrosative stress.mehr