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E-BookEPUBDRM AdobeE-Book
340 Seiten
Englisch
Elsevier Science & Techn.erschienen am24.07.2016

Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product.

The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders.

Presents the first 'Flowchart' of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner
Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc.
Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area
Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer
Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book
mehr

Produkt

Klappentext
Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product.

The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders.

Presents the first 'Flowchart' of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner
Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc.
Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area
Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer
Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book
Details
Weitere ISBN/GTIN9780444632661
ProduktartE-Book
EinbandartE-Book
FormatEPUB
Format HinweisDRM Adobe
Erscheinungsjahr2016
Erscheinungsdatum24.07.2016
Seiten340 Seiten
SpracheEnglisch
IllustrationenIllustrated
Artikel-Nr.3261437
Rubriken
Genre9200

Inhalt/Kritik

Inhaltsverzeichnis
1. Genetic Engineering in Stem Cell Manufacturing

2. Biomechanics in Stem Cell Manufacturing

3. Bioreactor Engineering Fundamentals for Stem Cell Manufacturing

4. Microcarrier Culture Systems for Stem Cell Manufacturing

5. Novel Single-Use Bioreactors for Scale up of Anchorage-Dependent Cell Manufacturing for Cell Therapies

6. Bioreactors and Downstream Processing for Stem Cell Manufacturing

7. Cell production system based on flexible modular platform

8. Microfluidic Devices for the Culture of Stem Cells

9. Enrichment and Separation Technologies for Stem Cell-Based Therapies

10. Expansion and Characterization Considerations for the Manufacturing of Stem Cells

11. Storage and Delivery of Stem Cells for Cellular Therapies

12. Business Models for Manufacture of Cellular Therapies

13. Stem cells for the regeneration of chronic wounds: a translational perspective
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Autor