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Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy

E-BookPDF1 - PDF WatermarkE-Book
150 Seiten
Englisch
Springer Berlin Heidelbergerschienen am06.12.20121998
This book gives an overview of the current state of the art in peripheral blood stem cell transplantation and recent developments in molecular diagnosis and gene therapeutic approaches. The focus is on the role of peripheral blood stem cell transplantation in the treatment of hematological malignancies such as non-Hodgkin lymphomas, chronic myelogenous leukemia and multiple myeloma. Current molecular biological techniques for detecting genetic defects in tumors and minimal residual disease are also presented. Further topics include new gene therapeutic concepts in hematology and oncology: the use of viral vectors for transduction of hematopoietic cells is discussed as well as therapeutic strategies based on antisense nucleic acids, ribozymes, and immunological approaches.mehr

Produkt

KlappentextThis book gives an overview of the current state of the art in peripheral blood stem cell transplantation and recent developments in molecular diagnosis and gene therapeutic approaches. The focus is on the role of peripheral blood stem cell transplantation in the treatment of hematological malignancies such as non-Hodgkin lymphomas, chronic myelogenous leukemia and multiple myeloma. Current molecular biological techniques for detecting genetic defects in tumors and minimal residual disease are also presented. Further topics include new gene therapeutic concepts in hematology and oncology: the use of viral vectors for transduction of hematopoietic cells is discussed as well as therapeutic strategies based on antisense nucleic acids, ribozymes, and immunological approaches.
Details
Weitere ISBN/GTIN9783642468360
ProduktartE-Book
EinbandartE-Book
FormatPDF
Format Hinweis1 - PDF Watermark
FormatE107
Erscheinungsjahr2012
Erscheinungsdatum06.12.2012
Auflage1998
ReiheRecent Results in Cancer Research
Reihen-Nr.144
Seiten150 Seiten
SpracheEnglisch
IllustrationenX, 150 p.
Artikel-Nr.7460024
Rubriken
Genre9200

Inhalt/Kritik

Inhaltsverzeichnis
Mobilization and Selection of CD34+ Cells.- Autologous Stem Cell Transplantation for Chronic Myeloid Leukemia.- Autologous Stem Cell Transplantation in Aggressive Non-Hodgkin's Lymphoma.- Peripheral Blood Progenitor Cell Transplantation in Multiple Myeloma Following High-Dose Melphalan-Based Therapy.- Molecular Monitoring of Residual Disease in Chronic Myelogenous Leukemia Patients After Therapy.- Delineation of Genomic Regions in Chromosome Band 7q22 Commonly Deleted in Myeloid Leukemias.- Molecular Cytogenetic Analysis of Low-Grade B-Cell Neoplasias: a Comparative Genomic Hybridization Study.- Applications of Gene Transfer in Hematologic Malignancy.- Dendritic Cells for Somatic Gene Therapy.- Construction of Immunogenic Tumor Cell Surfaces by Somatic Gene Transfer.- Adeno-associated Virus Type 2 Vector for Transduction of Hematopoietic Cells.- Protection of Hematopoietic Stem Cells from Chemotherapy-Induced Toxicity by Multidrug-Resistance 1 Gene Transfer.- Regulated Gene Expression After Retroviral Vector-Mediated Delivery of Cancer-Relevant Therapeutic Genes.- Specific bcr-abl-Directed Antisense Nucleic Acids and Ribozymes: A Tool for the Treatment of Chronic Myelogenous Leukemia?.- The Use of Ribozymes in Gene Therapy Approaches to AIDS.mehr

Autor