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Sex, Gender, and Epigenetics

From Molecule to Bedside
TaschenbuchKartoniert, Paperback
314 Seiten
Englisch
Elsevier Scienceerschienen am24.05.2023
Sex, Gender, and Epigenetics: From Molecule to Bedside explores our expanding knowledge of the science of epigenetics in which gene expression is modified as a consequence of small chemical additions to various components of the genome. The book provides an overview of the field, describing the epigenetic phenomena that unite biological sex and environmental experience to create the unique phenome of each individual. The book also analyzes the impact of ancestors´ environmental experience on subsequent generations through the sex-specific transmission of environmentally induced epigenetic modifications. Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, the microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics.mehr
Verfügbare Formate
TaschenbuchKartoniert, Paperback
EUR169,50
E-BookEPUBDRM AdobeE-Book
EUR155,00

Produkt

KlappentextSex, Gender, and Epigenetics: From Molecule to Bedside explores our expanding knowledge of the science of epigenetics in which gene expression is modified as a consequence of small chemical additions to various components of the genome. The book provides an overview of the field, describing the epigenetic phenomena that unite biological sex and environmental experience to create the unique phenome of each individual. The book also analyzes the impact of ancestors´ environmental experience on subsequent generations through the sex-specific transmission of environmentally induced epigenetic modifications. Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, the microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics.
Details
ISBN/GTIN978-0-12-823937-7
ProduktartTaschenbuch
EinbandartKartoniert, Paperback
FormatTrade Paperback (USA)
Erscheinungsjahr2023
Erscheinungsdatum24.05.2023
Seiten314 Seiten
SpracheEnglisch
MasseBreite 190 mm, Höhe 232 mm, Dicke 17 mm
Gewicht652 g
Artikel-Nr.59084316

Inhalt/Kritik

Inhaltsverzeichnis
1. Exploring how we become what we are2. A critical view of the revolution of precision medicine. Genetics, epigenetics, sex, and gender3. Genetic and epigenetic contributions to female-biased lupus disease: X-chromosome inactivation in immune cells4. Genetic, molecular, and cellular determinations of sex-specific cardiovascular traits5. Epigenetics and mental and physical health of children born after ART6. Epigenetic aspects of male infertility treatment7. Evidence for assisted reproductive technology associated epigenetic variation in humans8. Deconvoluting the functional role of DNA methylation in trauma; Implications for epigenetic therapy and prospects of targeted epigenetic therapy9. Antenatal Origins of Health and Disease-A clinician´s perspective10. Maternal anxiety during pregnancy and the lack of fetal DNA methylation in cord blood11. DNA methylation and other epigenetic modifications mediating the transgenerational impacts of paternal exposures on offspring phenotypes12. Epigenetics and psychiatry13. Integrative transcriptomics reveals sexually dimorphic control of the cholinergic/neurokine interface in schizophrenia and bipolar disorder14. Gender specific neurobehavioral and gene expression changes in a valproic acid (VPA)-induced mouse model of autistic like behavior and correction by S-adenosylmethionine (SAMe)15. Genetics and epigenetics of the onecarbon metabolism pathway in autism spectrum disorder: Role of a sex-specific brain epigenome16. Novel mechanisms for gene regulation: Chemical tags on RNA molecules17. Genes, environments, and epigenetics18. Epigenetic mechanisms linking poor maternal nutrition during pregnancy to the cardio-metabolic health of offspring19. Epigenetic aspects of human reproduction and early pregnancy20. Sex-specific impact of maternal metabolic environment on the development of the offspring, from gametogenesis to infancy and beyond21. Mitochondria as epigenetic regulators of reproductive aging22. The fetal programming of telomere biology hypothesis23. Brain organoids modeling of genetic and environmental impact on neurodevelopmental traitsmehr

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