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How Does Germline Regenerate?

TaschenbuchKartoniert, Paperback
176 Seiten
Englisch
University of Chicago Presserschienen am09.01.2024
A concise primer that complicates a convenient truth in biology-the divide between germ and somatic cells-with far-reaching ethical and public policy ramifications.   Scientists have long held that we have two kinds of cells-germ and soma. Make a change to germ cells-say using genome editing-and that change will appear in the cells of future generations. Somatic cells are safe after such tampering; modify your skin cells, and your future children´s skin cells will never know. And, while germ cells can give rise to new generations (including all of the somatic cells in a body), somatic cells can never become germ cells. How did scientists discover this relationship and distinction between somatic and germ cells-the so-called Weismann Barrier-and does it actually exist? Can somatic cells become germ cells in the way germ cells become somatic cells? That is, can germ cells regenerate from somatic cells even though conventional wisdom denies this possibility? Covering research from the late nineteenth century to the 2020s, historian and philosopher of science Kate MacCord explores how scientists came to understand and accept the dubious concept of the Weismann Barrier and what profound implications this convenient assumption has for research and policy, from genome editing to stem cell research, and much more.mehr
Verfügbare Formate
TaschenbuchKartoniert, Paperback
EUR28,00
E-BookEPUBDRM AdobeE-Book
EUR32,49

Produkt

KlappentextA concise primer that complicates a convenient truth in biology-the divide between germ and somatic cells-with far-reaching ethical and public policy ramifications.   Scientists have long held that we have two kinds of cells-germ and soma. Make a change to germ cells-say using genome editing-and that change will appear in the cells of future generations. Somatic cells are safe after such tampering; modify your skin cells, and your future children´s skin cells will never know. And, while germ cells can give rise to new generations (including all of the somatic cells in a body), somatic cells can never become germ cells. How did scientists discover this relationship and distinction between somatic and germ cells-the so-called Weismann Barrier-and does it actually exist? Can somatic cells become germ cells in the way germ cells become somatic cells? That is, can germ cells regenerate from somatic cells even though conventional wisdom denies this possibility? Covering research from the late nineteenth century to the 2020s, historian and philosopher of science Kate MacCord explores how scientists came to understand and accept the dubious concept of the Weismann Barrier and what profound implications this convenient assumption has for research and policy, from genome editing to stem cell research, and much more.
Details
ISBN/GTIN978-0-226-83051-3
ProduktartTaschenbuch
EinbandartKartoniert, Paperback
FormatTrade Paperback (USA)
Erscheinungsjahr2024
Erscheinungsdatum09.01.2024
Seiten176 Seiten
SpracheEnglisch
MasseBreite 140 mm, Höhe 216 mm, Dicke 10 mm
Gewicht227 g
Artikel-Nr.60363829

Inhalt/Kritik

Inhaltsverzeichnis
Introduction 1 Uncovering Assumptions That Have Shaped Germ Cell Science 2 Backgrounding Conflicts within Germ Cell Science 3 Challenging Assumptions in Germline Science 4 Implications of Reenvisioning Germline Regeneration Epilogue Acknowledgments Notes Bibliography Indexmehr