Hugendubel.info - Die B2B Online-Buchhandlung 

Merkliste
Die Merkliste ist leer.
Bitte warten - die Druckansicht der Seite wird vorbereitet.
Der Druckdialog öffnet sich, sobald die Seite vollständig geladen wurde.
Sollte die Druckvorschau unvollständig sein, bitte schliessen und "Erneut drucken" wählen.

Translational Surgery

TaschenbuchKartoniert, Paperback
768 Seiten
Englisch
Elsevier Science & Technologyerschienen am23.03.2023
Translational Surgery covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control studies, prospective cohort studies, randomized trials, and reliability studies. Investigators will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in surgical research, and know what is needed for collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the translational research navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in surgery, allowing the reader to learn how to evaluate the quality of such studies. Thus, they will improve at measuring outcomes; making effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every surgeon or surgical researcher who has ever had a good clinical idea, but not the knowledge of how to test it.mehr
Verfügbare Formate
TaschenbuchKartoniert, Paperback
EUR161,50
E-BookEPUBDRM AdobeE-Book
EUR144,00

Produkt

KlappentextTranslational Surgery covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control studies, prospective cohort studies, randomized trials, and reliability studies. Investigators will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in surgical research, and know what is needed for collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the translational research navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in surgery, allowing the reader to learn how to evaluate the quality of such studies. Thus, they will improve at measuring outcomes; making effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every surgeon or surgical researcher who has ever had a good clinical idea, but not the knowledge of how to test it.
Details
ISBN/GTIN978-0-323-90300-4
ProduktartTaschenbuch
EinbandartKartoniert, Paperback
Erscheinungsjahr2023
Erscheinungsdatum23.03.2023
Seiten768 Seiten
SpracheEnglisch
MasseBreite 279 mm, Höhe 215 mm, Dicke 40 mm
Gewicht2056 g
Artikel-Nr.59057974

Inhalt/Kritik

Inhaltsverzeichnis
1. Introduction; 2. Translational Process; 3. Scientific Method; 4. Basic Research Pre-Clinical 5. Overview of Preclinical Research; 6. What Problem Are You Solving?; 7. Types of Interventions; 8. Drug Discovery; 9. Drug Testing; 10. Device Discovery and Prototyping; 11. Medical Device Testing; 12. Diagnostic Discovery; 13. Diagnostic Testing; 14. Other Product Types; 15. Procedural Technique Development; 16. Behavioral Intervention Clinical: Fundamentals 17. Introduction to Clinical Research: What is it? Why is it needed?; 18. The Question: Types of Research Questions and How to Develop Them; 19. Study Population: Who and why them?; 20. Outcome Measurements: What data is being collected and why?; 21. Optimizing the question: Balancing significance and feasibility Statistical Principles; 22. Basic Statistical Principles; 23. Distributions; 24. Hypotheses and Error Types; 25. Power; 26. Regression; 27. Continuous Variable Analyses: T-test, Man Whitney, Wilcoxon Rank; 28. Categorical Variable Analyses: Chi-Square, fisher exact, Mantel Hanzel; 29. Analysis of Variance; 30. Correlation; 31. Biases; 32. Basic Science Statistics Clinical: Study Types 33. Design Principles: Hierarchy of Study Types; 34. Case Series: Design, Measures, Classic Example; 35. Case-Control: Design, Measures, Classic Example; 36. Cohort Study: Design, Measures, Classic Example; 37. Cross-Section Study: Design, Measures, Classic Example; 38. Longitudinal Study: Design, Measures, Classic Example; 39. Clinical Trials: Design, Measures, Classic Example; 40. Meta-Analysis: Design, Measures, Classic Example; 41. Cost-Effectiveness Study: Design, Measures, Classic Example; 42. Diagnostic Test Evaluation: Design, Measures, Classic Example; 43. Reliability Study: Design, Measures, Classic Example; 44. Database Studies: Design, Measures, Classic Example; 45. Surveys and Questionnaires: Design, Measures, Classic Example; 46. Qualitative Methods and Mixed Methods Clinical Trials 47. Randomized Control: Design, Measures, Classic Example; 48. Nonrandomized Control: Design, Measures, Classic Example; 49. Historical Control: Design, Measures, Classic Example; 50. Cross-Over: Design, Measures, Classic Example; 51. Withdrawal Studies: Design, Measures, Classic Example; 52. Factorial Design: Design, Measures, Classic Example; 53. Group Allocation: Design, Measures, Classic Example; 54. Hybrid Design: Design, Measures, Classic Example; 55. Large, Pragmatic: Design, Measures, Classic Example; 56. Equivalence and Noninferiority: Design, Measures, Classic Example; 57. Adaptive: Design, Measures, Classic Example; 58. Randomization: Fixed or Adaptive Procedures; 59. Blinding: Who and How?; 60. Multicenter Considerations; 61. Registries; 62. Phases of Clinical Trials; 63. IDEAL Framework; 64. Artificial Intelligence; 65. Patient Perspectives Clinical: Preparation 66. Sample Size; 67. Budgeting; 68. Medical Ethics and Review Boards; 69. Regulatory Considerations for New Drugs and Devices; 70. Funding Approaches; 71. Subject Recruitment; 72. Data Management; 73. Quality Control; 74. Statistical Software; 75. Report Forms: Harm and Quality of Life; 76. Subject Adherence; 77. Survival Analysis; 78. Monitoring Committee in Clinical Trials Regulatory Basics 79. FDA Overview; 80. IND; 81. New Drug Application; 82. Devices; 83. Radiation-emitting Electronic Products; 84. Orphan Drugs; 85. Biologics; 86. Combination Products; 87. Foods; 88. Cosmetics; 89. Non-US Regulatory Clinical Implementation 90. Implementation Research; 91. Design and Analysis; 92. Population and Setting Specific Implementation Public Health 93. Public Health; 94. Epidemiology; 95. Factors in Surgical Public Health and Health Disparities Research; 96. Good Questions; 97. Population and Environmental Specific Considerations; 98. Law, Policy, and Ethics; 99. Healthcare Institutions and Systems; 100. Public Health Institutions and Systems Practical Resources 101. Presenting Data; 102. Manuscript Preparation; 103. Building a Team; 104. Patent Basics; 105. Venture Pathways; 106. SBIR/STTR; 107. Sample Forms and Templatesmehr