Molecular Basis of Neurological Disorders and Their Treatment

von

Gorrod, J. W.Albano, A.Papa, S.

BuchGebunden

337 Seiten

Englisch

Springer Netherlandserschienen am30.06.1991

A particular advantage of a cytochemical approach to the investiga tion of mitochondrial disorders is that it allows the mosaic distribution of certain of these defects to be detected, whereas the tissue homogeniza tion involved in conventional enzyme assays or immunoblotting precludes this.mehr

Verfügbare Formate

BuchGebunden

EUR213,99

BuchKartoniert, Paperback

EUR213,99

E-BookPDF1 - PDF WatermarkE-Book

EUR213,99

Auf dieser Seite:

EUR213,99

In den Warenkorb

Produkt

KlappentextA particular advantage of a cytochemical approach to the investiga tion of mitochondrial disorders is that it allows the mosaic distribution of certain of these defects to be detected, whereas the tissue homogeniza tion involved in conventional enzyme assays or immunoblotting precludes this.

Details

ISBN/GTIN978-0-412-40410-8

ProduktartBuch

EinbandartGebunden

Verlag

Springer Netherlands

Erscheinungsjahr1991

Erscheinungsdatum30.06.1991

Seiten337 Seiten

SpracheEnglisch

Gewicht676 g

IllustrationenXV, 337 p.

Artikel-Nr.10831980

Rubriken

GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis

1 Towards a molecular model of the acetylcholine receptor channel.- 2 Proton-motive ATP synthase and energy transfer in the cell.- 3 Comparative analysis of the amount of subunit I and subunit IV of the cytochrome c oxidase mRNAs in the cerebral hemispheres of senescent rat and effect of acetyl-l-carnitine.- 4 Cytochemical and immunocytochemical investigation of respiratory complexes in individual fibres of human skeletal muscle.- 5 Native myelin proteins and myelin assembly in the central nervous system.- 6 Regulation of immune cells by serine phospholipids.- 7 Cell adhesion molecules belonging to the immunoglobulin superfamily.- 8 Neurogenic control of cerebral blood vessels.- 9 The fine structural aspects of brain oedema and associated microvascular and glial changes.- 10 Image-guided localized nuclear magnetic resonance spectroscopy of human brain tumours.- 11 Neuroimaging study of frontal lobes.- 12 Biochemical indicators of ischaemic brain damage.- 13 Molecular basis of astroglial reaction to brain injury; regulation of glial fibrillary acidic protein mRNA in rat cerebral cortex and in primary astroglial cell cultures.- 14 Tissue plasminogen activator; acute thrombotic stroke.- 15 Lysosomal storage of a mitochondrial protein in Batten´s disease (ceroid lipofuscinosis).- 16 Leber´s hereditary optic neuropathy; from the clinical to the new biochemical and molecular findings for understanding the pathogenesis of the disorder.- 17 Types and mechanism of mitochondrial DNA mutations in mitochondrial myopathy and related diseases.- 18 Direct tandem duplications of mitochondrial DNA in mitochondrial myopathy.- 19 Mutations of mitochondrial DNA; the molecular basis of mitochondrial encephalomyopathies and ageing.- 20 Analysis of giant deletions of human mitochondrialDNA in progressive external opthalmoplegia.- 21 Biochemical and genetic investigations in eleven cases of mitochondrial myopathies.- 22 Familiar cases of mitochondrial myopathies; mitochondrial DNA deletions and genetic analysis.- 23 The correlation between pathology, biochemistry and molecular genetics in mitochondrial encephalomyopathies.- 24 Various clinical presentation of mytochondriopathies; clinical and therapeutic considerations.- 25 Voltage-gated sodium channels as target for pharmacologic agents.- 26 A K+ channel opener in vascular smooth muscle; pharmacology and mechanism of action of cromakalim.- 27 Molecular and cellular mechanisms involves in high resistance neonatal brain resistance to anoxia.- 28 Metabolic activation and mechanisms of MPTP toxicity.- 29 Neurochemical changes produced by perinatal exposure to lead.- 30 Electrophoretic studies of the interaction of neuroleptic drugs with brain tissue.mehr