Biological Models in Radiopharmaceutical Development

von

Lambrecht, R. M.

BuchGebunden

272 Seiten

Englisch

Springer Netherlandserschienen am31.12.1995

Radiophannaceuticals labeled with short-lived radionuclides are utilized to unravel biochemical processes, and to diagnosis and treat diseases of the living body are-developed through extensive evaluation in ~iological models.mehr

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KlappentextRadiophannaceuticals labeled with short-lived radionuclides are utilized to unravel biochemical processes, and to diagnosis and treat diseases of the living body are-developed through extensive evaluation in ~iological models.

Details

ISBN/GTIN978-0-7923-3836-9

ProduktartBuch

EinbandartGebunden

Verlag

Springer Netherlands

Erscheinungsjahr1995

Erscheinungsdatum31.12.1995

Seiten272 Seiten

SpracheEnglisch

Gewicht679 g

IllustrationenXI, 272 p.

Artikel-Nr.13732175

Rubriken

GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis

Preface.- Acknowledgements.- Scope of the Work.- Guidelines for Research with Animals.- Moral and Ethical Considerations.- Principles and Training Programs.- Design of Candidate Radiopharmaceuticals.- Identification of Clinical Need.- Choice of Radionuclide.- Screening Studies.- Drug Development.- Concept of Biological Model.- In Vitro Models.- Choice of Biological Models.- Species Variations.- Transgenic Mice.- Dogs and Kangaroos.- Poison Arrow Frog.- Giraffe.- Tomographic Phisiological Chemistry.- ARG.- SPET.- PET.- SIMS.- Keyword Guide to Selection of Biological Models.- References.- Glossary of Abbreviations.mehr

Kritik

`This is an original and unique reference book with high practical value for researchers in the field. Those who have dealt with the problem of finding an appropriate animal model for a certain study will especially appreciate this book. This book is an absolute `must' for those involved in preclinical development and biological testing of radiopharmaceuticals.'
European Journal of Nuclear Medicine, 23:7 (1996)mehr