Munther A. Khamashta, MD, FRCP, PhD is the Director of the Lupus Unit in the St Thomas Hospital of London, UK. Dr Munther Khamashta was born in Bethlehem (Palestine). He studied medicine in Barcelona, Spain and trained in internal medicine in Madrid, Spain. Due to his interest in connective tissue diseases, he joined the Lupus Unit at St. Thomas´ in 1986 and has since worked tirelessly for the unit both clinically and in research. He runs a large Lupus pregnancy clinic and has published over 500 clinical and research studies in lupus, antiphospholipid syndrome, vasculitis, Sjögren syndrome and related conditions. Manuel Ramos-Casals MD, PhD is a Consultant of the Department of Systemic Autoimmune Diseases, Head of the "Josep Font" Laboratory of Autoimmune Diseases of the IDIBAPS , Hospital Clínic, Barcelona, and Assistant Professor, Department of Medicine, University of Barcelona, Barcelona, Spain. He has published more than 100 original articles focused on Sjögren´s syndrome and related conditions, has edited 6 books on systemic autoimmune diseases and has received several national grants to investigate autoimmune diseases.The Editors have extensive experience in the management of the main systemic autoimmune diseases, such as systemic lupus erythematosus, antiphospholipid syndrome, vasculitis, scleroderma, Sjögren´s syndrome and biological therapies. They have developed many clinical and basic research projects and, in the last 5 years, have published many reports in the leading journals in rheumatology and internal medicine.