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Animal Models of Diabetes

Methods and Protocols
BuchGebunden
342 Seiten
Englisch
Springererschienen am17.03.20201st ed. 2020
This volume discusses a variety of animal models of diabetes, as well as describes techniques used to study end-points when using these models.mehr
Verfügbare Formate
BuchGebunden
EUR160,49
BuchKartoniert, Paperback
EUR128,39
E-BookPDF1 - PDF WatermarkE-Book
EUR119,99

Produkt

KlappentextThis volume discusses a variety of animal models of diabetes, as well as describes techniques used to study end-points when using these models.
Zusammenfassung
Includes cutting-edge methods and protocols

Provides step-by-step detail essential for reproducible results

Contains key notes and implementation advice from the experts
Details
ISBN/GTIN978-1-0716-0384-0
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2020
Erscheinungsdatum17.03.2020
Auflage1st ed. 2020
ReiheMethods in Molecular Biology
Seiten342 Seiten
SpracheEnglisch
Gewicht840 g
IllustrationenXI, 342 p. 49 illus., 39 illus. in color.
Artikel-Nr.54440572
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
Practical Considerations when Using Mouse Models of Diabetes.- An Overview of Rodent Models of Obesity and Type 2 Diabetes.- Selectively Bred Diabetes Models: GK Rats, NSY Mice, and ON Mice.- A Review of Mouse Models of Monogenic Diabetes and ER Stress Signalling.- Rat Models of Human Type 1 Diabetes.- Mouse Models of Autoimmune Diabetes: The Non-Obese Diabetic (NOD) Mouse.- Mouse Models of Virus-Induced Type 1 Diabetes.- Rat Models of Virus-Induced Type 1 Diabetes.- Large Animal Models of Diabetes.- Use of Streptozotocin in Rodent Models of Islet Transplantation.- Transplantation of Islets of Langerhans into the Anterior Chamber of the Eye for Longitudinal In Vivo Imaging.- Multicolor Labeling and Tracing of Pancreatic Beta-Cell Proliferation in Zebrafish.- Generating Beta-Cell Specific Transgenic Mice Using the Cre-Lox System.- The Glucose Tolerance Test in Mice.- Assessment of Insulin Tolerance In Vivo in Mice.- Continuous Glucose Monitoring in Conscious Unrestrained Mice.- Assessing Mouse Islet Function.- Assessing Immune Responses in the Nonobese Diabetic Mouse Model of Type 1 Diabetes.- Assessment of Insulin Tolerance Ex Vivo.- Using Pancreas Tissue Slices for the Study of Islet Physiology.- Determining Beta Cell Mass, Apoptosis, Proliferation, and Individual Beta Cell Size in Pancreatic Sections.mehr