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Narcolepsy

Pathophysiology, Diagnosis, and Treatment
BuchGebunden
428 Seiten
Englisch
Springererschienen am01.07.2011
Narcolepsy: Pathophysiology, Diagnosis, and Treatment not only offers an engaging and comprehensive treatment of a fascinating disorder but also includes a DVD that offers a unique and large collection of movies displaying the symptoms of narcolepsy in people and animals.mehr
Verfügbare Formate
BuchGebunden
EUR181,89
E-BookPDF1 - PDF WatermarkE-Book
EUR171,19

Produkt

KlappentextNarcolepsy: Pathophysiology, Diagnosis, and Treatment not only offers an engaging and comprehensive treatment of a fascinating disorder but also includes a DVD that offers a unique and large collection of movies displaying the symptoms of narcolepsy in people and animals.
ZusammenfassungNarcolepsy: Pathophysiology, Diagnosis, and Treatment offers an engaging and comprehensive overview of this fascinating disorder. The text focuses on the pathophysiology of the problem but also provides critical, up-to-date insights on the key clinical issues.
Details
ISBN/GTIN978-1-4419-8389-3
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2011
Erscheinungsdatum01.07.2011
Seiten428 Seiten
SpracheEnglisch
Gewicht1120 g
IllustrationenXVI, 428 p. 81 illus., 12 illus. in color.
Artikel-Nr.10285188
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
Etiology and genetics of human narcolepsy.- Narcolepsy: autoimmunity or secondary to infection?.- Is narcolepsy a neurodegenerative disorder?.- The roles of hypocretin/orexin in narcolepsy, Parkinson´s disease, and normal behaviour.- Histamine in narcolepsy and excessive daytime sleepiness.- Dopaminergic substrates underlying hypersomnia, sleepiness, and REM sleep expression.- The serotoninergic system in sleep and narcolepsy.- Sleep homeostasis, adenosine, caffeine, and narcolepsy.- Prostaglandin D2: an endogenous somnogen.- The neurobiology of sleep-wake systems: an overview.- The hypocretins/orexins: master regulators of arousal and hyperarousal.- Optogenetic probing of hypocretin/orexin regulation of wakefulness.- Hypocretin/orexin receptor functions in mesopontine systems regulating sleep, arousal and cataplexy.- Afferent control of the hypocretin/orexin neurons.- The neural basis of sleepiness in narcoleptic mice.- Mathematical models of narcolepsy.- The hypothalamus and its functions.- The prehistory of orexin/hypocretin and melanin-concentrating hormone neurons of the lateral hypothalamus.- Metabolic influence on the hypocretin/orexin neurons.- Endocrine abnormalities in narcolepsy.- Appetite and obesity.- Effects of orexin/hypocretin on ventral tegmental area dopamine neurons: an emerging role in addiction.- Orexin/hypocretin, drug addiction, and narcolepsy.- Emotional processing in narcolepsy.- Depression in narcolepsy.- The clinical features of cataplexy.- Parasomnias in narcolepsy with cataplexy.- The motor system and narcolepsy: Periodic leg movements and restless leg syndrome.- Spectrum of narcolepsy.- Secondary narcolepsy.- Posttraumatic narcolepsy.- The hypocretin/orexin system and sleepiness in Parkinson´s disease.- Idiopathic hypersomnia.- Current diagnostic criteria of adult narcolepsy.- The arguments for standardized diagnostic procedures.- Fitness to drive in narcolepsy.- Treatment of narcolepsy.- Treatment of narcolepsy in thechildmehr
Kritik
From the reviews:
"This comprehensive review of narcolepsy, written by scientific experts in the field of sleep disorders research and medicine, serves as guide to understanding its etiology, pathophysiology, and clinic treatment. ... It is targeted primarily for sleep researchers and clinicians, as well as those who have a specific interest in narcolepsy. ... With its in-depth analysis of the important areas of the etiology, diagnosis, prognosis, treatment, and management of narcolepsy, this is a useful compendium for both scientists and clinicians." (Maureen A. Smith, Doody's Review Service, January, 2012)mehr

Autor

Christian R. Baumann, MD
University Hospital of Zurich, Switzerland

Claudio L. Bassetti, MD
University Hospital of Zurich, Switzerland

Thomas E. Scammell, MD
Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, USA
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