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BuchGebunden
472 Seiten
Englisch
Springererschienen am16.07.2012
This book covers the various methods of validation for high performance liquid chromatography - mass spectrometry (LC-MS) analytical techniques and their applications in the analysis of a broad range of drugs in modern clinical pharmacology.mehr
Verfügbare Formate
BuchGebunden
EUR106,99
BuchKartoniert, Paperback
EUR106,99
E-BookPDF1 - PDF WatermarkE-Book
EUR96,29

Produkt

KlappentextThis book covers the various methods of validation for high performance liquid chromatography - mass spectrometry (LC-MS) analytical techniques and their applications in the analysis of a broad range of drugs in modern clinical pharmacology.
Details
ISBN/GTIN978-1-4614-3827-4
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2012
Erscheinungsdatum16.07.2012
Seiten472 Seiten
SpracheEnglisch
Gewicht860 g
IllustrationenXII, 472 p.
Artikel-Nr.17485965

Inhalt/Kritik

Inhaltsverzeichnis
Internal standards for quantitative LC-MS bioanalysis.- Method development, validation and sample analysis for regulated quantitative bioanalysis using LC-MS/MS.- Impact of sampling paper/cards on bioanalytical quantitation via dried blood spots by liquid chromatography - mass spectrometry.- Highly sensitive pharmaceutical and clinical analysis using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry.- Pitfalls of LC-MS/MS in the clinical laboratory.- Therapeutic drug monitoring to support clinical pharmacogenomics.- Liquid chromatography - mass spectrometry for the determination of antidepressants and some of their major metabolites in human biological matrices.- The analysis of antipsychotic drugs in human biosamples by LC-MS.- Therapeutic drug monitoring of targeted anticancer therapy - tyrosine kinase inhibitors and selective oestrogen receptor modulators: a clinical pharmacology laboratory perspective.- Applications of mass spectrometry in analyses of steroid hormones.- Liquid chromatography - mass spectrometric analysis of tropane alkaloids in mammalian samples: techniques and applications.- Analysis of illicit drugs in human biological samples by LC-MSn.- Use of matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) in the development of novel small molecule drugs.- A planar integrated micro mass spectrometer.mehr

Schlagworte