Gene Essentiality

Methods and Protocols - Previously published in hardcover

von

Herausgegeben von Lu, Long Jason

BuchKartoniert, Paperback

248 Seiten

Englisch

Springererschienen am05.10.2016Softcover reprint of the original 1st ed. 2015

This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans.mehr

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Produkt

KlappentextThis volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans.

Details

ISBN/GTIN978-1-4939-4862-8

ProduktartBuch

EinbandartKartoniert, Paperback

Verlag

Springer

Erscheinungsjahr2016

Erscheinungsdatum05.10.2016

AuflageSoftcover reprint of the original 1st ed. 2015

ReiheMethods in Molecular Biology

Seiten248 Seiten

SpracheEnglisch

Gewicht555 g

IllustrationenXI, 248 p. 42 illus., 15 illus. in color.

Artikel-Nr.40395894

Rubriken

GenreMedizin

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Inhalt/Kritik

Inhaltsverzeichnis

Microarray Transposon Tracking for the Mapping of Conditionally Essential Genes in Campylobacter jejuni.- Identifying Essential Streptococcus sanguinis Genes Using Genome-Wide Deletion Mutation.- Defining Essential Genes and Identifying Virulence Factors of Porphyromonas gingivalis by Massively-Parallel Sequencing of Transposon Libraries (Tn-seq).- Identification of Essential Genes and Synthetic Lethal Gene Combinations in Escherichia coli K-12.- Identification of Genes Essential for Leptospirosis.- Identifying Essential Genes in Mycobacterium tuberculosis by Global Phenotypic Profiling.- Essential Genes in the Infection Model of Pseudomonas aeruginosa-PCR-Based Signature-Tagged Mutagenesis.- Genome-Wide Synthetic Genetic Screening by Transposon Mutagenesis in Candida albicans.- An Integrated Machine-Learning Model to Predict Prokaryotic Essential Genes.- A Statistical Framework for Improving Genomic Annotations of Transposon Mutagenesis (TM) Assigned Essential Genes.- A Proposed Essential Gene Discovery Pipeline: A Campylobacter jejuni Case Study.- Computational Prediction of Essential Metabolic Genes Using Constraint-Based Approaches.- Three Computational Tools for Predicting Bacterial Essential Genes.- Gene Essentiality Analysis Based on DEG 10, an Updated Database of Essential Genes.- A Novel Essential Domain Perspective for Exploring Gene Essentiality.mehr