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Adeno-Associated Virus Vectors

Design and Delivery - Book w. online files / update
BuchGebunden
426 Seiten
Englisch
Springererschienen am20.02.20191st ed. 2019
Novel techniques such as ultrasound-targeted delivery to the brain, subpial delivery to the spinal cord, and subILM delivery to the retina are accompanied by chapters that provide an overview and comparison of current methods for AAV delivery to tissues such as brain, heart, liver, and lung.mehr
Verfügbare Formate
BuchGebunden
EUR213,99
E-BookPDF1 - PDF WatermarkE-Book
EUR213,99

Produkt

KlappentextNovel techniques such as ultrasound-targeted delivery to the brain, subpial delivery to the spinal cord, and subILM delivery to the retina are accompanied by chapters that provide an overview and comparison of current methods for AAV delivery to tissues such as brain, heart, liver, and lung.
Zusammenfassung
Includes cutting-edge techniques

Provides step-by-step detail essential for reproducible results

Contains key implementation advice from the experts
Details
ISBN/GTIN978-1-4939-9138-9
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2019
Erscheinungsdatum20.02.2019
Auflage1st ed. 2019
ReiheMethods in Molecular Biology
Seiten426 Seiten
SpracheEnglisch
Gewicht989 g
IllustrationenXII, 426 p. 62 illus., 50 illus. in color. With online files/update.
Artikel-Nr.46085411
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
1. Design of AAV vectors for Delivery of RNAi.- 2. Design of AAV Vectors for Delivery of Large or Multiple Transgenes.- 3. Ligand Coupling to the AAV Capsid for Cell-Specific Gene Transfer.- 4. Quantitative and Digital Droplet-based AAV Genome Titration.- 5. Single-Stranded DNA Virus Sequencing (SSV-Seq) for Characterization of Residual.- 6. In Situ Hybridization for Detection of AAV-Mediated Gene Expression.- 7. Use of AAV Vectors for CRISPR-Mediated In Vivo Genome Editing in the Retina.- 8. Intravenous Infusion of AAV for Widespread Gene Delivery to the Nervous System.- 9. Intraspinal and Intracortical Delivery of AAV Vectors for Intersectional Circuit Tracing in Non-Transgenic Species.- 10. MRI-Guided Focused Ultrasound for Targeted Delivery of rAAV to the Brain.- 11. AAV-Mediated Gene Delivery to the Spinal Cord by Intrathecal Injection.- 12. Subpial AAV Delivery for Spinal Parenchymal Gene Regulation in Adult Mammals.- 13. Peripheral AAV Injection for Retrograde Transduction of Dorsal Root and Trigeminal Ganglia.- 14. SubILM Injection of AAV for Gene Delivery to the Retina.- 15. Intracameral Delivery of AAV to Corneal Endothelium for Expression of Secretory Proteins.- 16. AAV-Mediated Gene Delivery to the Inner Ear.- 17. Intranasal Delivery of Adenoviral and AAV Vectors for Transduction of the Mammalian Peripheral Olfactory System.- 18. AAV-Mediated Gene Delivery to Taste Cells of the Tongue.- 19. AAV Vectors for Efficient Gene Delivery to Rodent Hearts.- 20. AAV-Mediated Gene Delivery to the Liver: Overview of Current Technologies and Methods.- 21.- AAV-Mediated Gene Delivery to the Lung.- 22. Simplified Purification of AAV and Delivery to the Pancreas by Intraductal Administration.- 23. rAAV-Mediated Gene Delivery to Adipose Tissue.- 24. AAV-Mediated Gene Delivery to the Enteric Nervous System by Intracolonic Injection.mehr