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Biostatistics in Biopharmaceutical Research and Development

Clinical Trial Analysis, Volume 2
BuchGebunden
440 Seiten
Englisch
Springererscheint am17.11.20242024
Volume 2 covers Biomarkers in Drug Development, Time-To-Event Data Analysis and Methods, and emerging development in biopharmaceutical biostatistics.This book aims to booster research, education, and training in biostatistics and in biopharmaceutical research and development.mehr
Verfügbare Formate
BuchGebunden
EUR213,99
BuchGebunden
EUR213,99

Produkt

KlappentextVolume 2 covers Biomarkers in Drug Development, Time-To-Event Data Analysis and Methods, and emerging development in biopharmaceutical biostatistics.This book aims to booster research, education, and training in biostatistics and in biopharmaceutical research and development.
Details
ISBN/GTIN978-3-031-65936-2
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2024
Erscheinungsdatum17.11.2024
Auflage2024
Seiten440 Seiten
SpracheEnglisch
IllustrationenApprox. 450 p. 50 illus.
Artikel-Nr.56451485

Inhalt/Kritik

Inhaltsverzeichnis
Statistical Challenges in the Analysis of Biomarker Data.- 2.    Evaluating Predictive Accuracy of Prognostic Model for Censored Time-to-Event Data Analysis in Clinical Trials.- Statistical Methods for Accommodating Immortal Time: A Selective Review and Comparison.- Variable selection for partially functional additive Cox Model with interval-censored failure time data.- A Bayesian proportional hazards model to predict patient recruitment in multicenter clinical trials.- GET MORE INFORMATION FROM RECURRENT EVENTS DATA.- Introduction to Patient Preference Studies.- Machine Learning for Precision Medicine and Humanized AI for Future Healthcare.- The Statistical Evaluation of Surrogate Endpoints in Clinical Trialsâââââââ.- Treatment Effect Estimation Using Data from Observational and Non-Randomized Studiesâââââââ.- Methods for Comparing Two Treatments for a Dichotomous Outcome for a Two-Period Design with Treatment Switching of Control Group Period 1 Non-Responders.- Regression-based estimation of optimal adaptive treatment strategies: Key methodsâââââââ.- Vaccine Disease-Prevention Efficacy Studies: Traditional Approaches and New Frontiersâââââââ.- Covariate Adjustment in Analyzing Randomized Clinical Trials: Approaches, Software, and Applicationâââââââ.- Joint correlated responses and feedback effect with time-dependent covariates.- Distributions and Their Approximations for P-Values.mehr

Autor

Dr. Ding-Geng Chen is a Fellow of the American Statistical Association and is currently the executive director and professor in biostatistics at the College of Health Solutions, Arizona State University. He is also an Extraordinary Professor and the SARChI in biostatistics at the University of Pretoria, and an honorary professor at the University of KwaZulu-Natal, South Africa. He is a senior biostatistics consultant for biopharmaceuticals and government agencies with extensive expertise in biostatistics, clinical trials, and public health statistics. Dr. Chen has more than 200 referred professional publications and co-authored 11 books and co-edited 24 books on clinical trial methodology, meta-analysis, data science, causal inference, and public health research. Professor Chen is the Deming publicity chair and he has been honored with the "Award of Recognition" from the Deming Conference Committee for highly successful advanced biostatistics workshop tutorials with his books.