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BuchGebunden
474 Seiten
Englisch
Springererschienen am11.10.20171st ed. 2017
The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments.mehr
Verfügbare Formate
BuchKartoniert, Paperback
EUR181,89
BuchGebunden
EUR181,89
E-BookPDF1 - PDF WatermarkE-Book
EUR171,19

Produkt

KlappentextThe content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments.
Zusammenfassung
Comparative bone biology of animal species commonly used in toxicology studies with humans

Special considerations highlighted for Juvenile toxicology

Collection of chapters on bone interactions with other organ systems

Includes supplementary material: sn.pub/extras
Details
ISBN/GTIN978-3-319-56190-5
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2017
Erscheinungsdatum11.10.2017
Auflage1st ed. 2017
ReiheMolecular and Integrative Toxicology
Seiten474 Seiten
SpracheEnglisch
Gewicht884 g
IllustrationenXII, 474 p. 72 illus., 63 illus. in color.
Artikel-Nr.42527319
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
Bone Toxicology in Preclinical Drug Testing.- Bone Physiology and Biology.- Study designs and Regulatory Considerations.- Specific Considerations for Bone Evaluations for Pediatric Therapeutics.- Bone Pharmacology and other models in Preclinical Drug Testing.- Methods in Bone Toxicology.- Biochemical Markers and Hormones.- Imaging.- Biomechanics.- Pathology and Histomorphometry.- Integrated System Toxicology.- Bone and Muscle.- Bone and Reproductive System.- Bone and Kidneys.- Bone and Energy Metabolism.- Bone and Immune System.- Bone and Central Nervous System.- Bone and Other Organs.mehr

Schlagworte

Autor

Susan Y. Smith is a consultant who specializes in nonclinical muscoloskeletal research. She provides guidance for the conduct of pharmacology, efficacy or safety studies, or help with data interpretation to unravel the mysteries of skeletal evaluations. She received a Master of Science in Pharmacology at McGill University and later joined Charles River Laboratories for almost 18 years and where she became Senior Scientific Director of Musculoskeletal Research. She has over 30 years of experience in preclinical safety assessments and toxicology and over 20 years of expertise in bone research.
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