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Insights into Receptor Function and New Drug Development Targets

BuchGebunden
202 Seiten
Englisch
Springererschienen am25.07.2006
Discusses receptor function in the development of new drugs. This title reviews the availability of tools that allow measurement of interactions and afford unprecedented insight into the biomolecular interactions that present approaches to drug design.mehr
Verfügbare Formate
BuchGebunden
EUR106,99
BuchKartoniert, Paperback
EUR106,99
E-BookPDF1 - PDF WatermarkE-Book
EUR96,29

Produkt

KlappentextDiscusses receptor function in the development of new drugs. This title reviews the availability of tools that allow measurement of interactions and afford unprecedented insight into the biomolecular interactions that present approaches to drug design.
Details
ISBN/GTIN978-3-540-34446-9
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2006
Erscheinungsdatum25.07.2006
Seiten202 Seiten
SpracheEnglisch
Gewicht444 g
IllustrationenXV, 202 p.
Artikel-Nr.10713762
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
Molecular and functional diversity of the TRPC family of ion channels. TRPC channels and their role in ROCE/SOCE.- Functional Rescue of Misfolded Receptor Mutants.- Obesity-related mutations of leptin and melanocortin receptors.- cAMP- and cGMP-dependent control of lipolysis and lipid mobilization in humans: putative targets for fat cell management.- Central Neuropeptide Receptors Involved in Water Balance: Application to Apelin.- Targeting regulators of G protein signaling (RGS proteins) to enhance agonist specificity.- Dimeric GPCRs: what did we learn from the metabotropic glutamate receptors?.- Guiding principles applied in the design of GPCR-selective hypothalamic hormone agonists and antagonists.- Mutations in G proteins and G protein-coupled receptors in human endocrine diseases.- A molecular dissection of the glycoprotein hormone receptors.- Receptor Tyrosine Kinases as Targets for Cancer Therapy Development.- Targets for pituitary tumor therapy.- The endogenous cannabinoid system in the control of food intake and energy balance.mehr