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Stem Cell Aging: Mechanisms, Consequences, Rejuvenation

BuchGebunden
354 Seiten
Englisch
Springererschienen am15.07.20151st ed. 2015
Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging.mehr
Verfügbare Formate
BuchKartoniert, Paperback
EUR106,99
BuchGebunden
EUR106,99
E-BookPDF1 - PDF WatermarkE-Book
EUR96,29

Produkt

KlappentextAging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging.
ZusammenfassungThis book offers insight into stem cell function, comprehensively exploring the mechanisms of stem cell aging in model organisms and mammalian systems, and describing related diseases and approaches for attenuating stem cell aging or attaining rejuvenation.
Details
ISBN/GTIN978-3-7091-1231-1
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2015
Erscheinungsdatum15.07.2015
Auflage1st ed. 2015
Seiten354 Seiten
SpracheEnglisch
Gewicht727 g
IllustrationenXI, 354 p. 33 illus., 32 illus. in color.
Artikel-Nr.17620778

Inhalt/Kritik

Inhaltsverzeichnis
Introduction.- Stem cells, aging and longevity (overview).- General mechanisms of stem cell aging (overview).- Mechanisms of Stem Cell Aging in Model Organisms.- Yeast: Chronological aging.- Divisional aging.- Primarily germline.- stem cell aging.- Drosophila: Male germ line.- Female germ line.- Somatic stem cells (stress and regulation of hematopoietic precursors, intestinal stem cell aging and regulation). Zebrafish.- Mechanisms of Stem Cell Aging in Mammalian Tissues.-Hematopoietic (Mouse/Human).- Skin (Mouse/Human).- Intestine (Mouse/Human).- Muscle (Mouse/Human).- Neuronal Tissues (Mouse/Human).- Diseases of Aging and Stem Cells.- Chronic Myeloid Leukemia and Aging of Hematopoietic Stem Cells (Mouse/Human).- Wound Healing Repair and Aging of Skin Stem Cells (Mouse/Human).- Stem Cell Rejuvenation Muscle.- Hematopoietic.- Neuronal.mehr
Kritik
"This book discusses the impact of aging on the many stem cell populations, the pathologies associated with the decline of stem cell functions, and the use of stem cells to attenuate stem cell aging. ... The purpose is to provide a reference for researchers working in the field of healthy aging. The audience is clinicians and all scientists working in the field of aging, stem cells, and regenerative medicine." (Michele Fornaro, Doody's Book Reviews, October, 2015)mehr

Autor


Hartmut Geiger studied chemistry and biochemistry at the Universities of Karlsruhe and Witten/Herdecke in Germany. He received his PhD from the Max-Planck-Institute for Immunobiology in Freiburg, Germany in 1999. From 1999 to 2002  he was scientific research fellow at the University of Kentucky, USA with expertise in stem cells, genetics and aging. From 2002 to 2008 he was Assistant Professor at the Division of Experimental Hematology, Cincinnati Children´s Hospital Medical Center, University of Cincinnati, USA. Since 2008 he has been Associate Professor at the University of Cincinnati, USA and Professor at the University of Ulm, Division of Dermatology and Allergic Diseases, Germany. His main research interest lies in the molecular biology of aging.
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