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Natural Iron Chelators: Safety and Efficacy Trials

Großformatiges Paperback. Klappenbroschur
BuchKartoniert, Paperback
336 Seiten
Englisch
Scholars' Presserschienen am04.04.2023
Iron overload is the accumulation of excess iron in body tissues and Hemochromatosis is a disease that occurs as a result of significant iron overload. Hereditary hemochromatosis is the genetic disease that results from significant iron overload. Acquired iron overload occurs when one obtains excessive amounts of iron from repeated exposure through supplementation, diet, iron shots, blood transfusion. Excess of iron gets deposited in vital organs and tissues such as liver, brain, heart, spleen and bones and leads to problems. The management of iron overload can be divided in to two types mainly.a. Phlebotomy b. Iron Chelationa. Phlebotomy: A phlebotomy is a procedure used to remove blood from a person.b. Iron Chelation: The available treatment for iron Chelation is either having many side effects or is very costly. Patients cannot tolerate the side effects of the daily injections. No ideal chelator exists to treat patients with transfusional iron overload. Still the search for is needed and such a compound can be extrapolated from the clinical requirements: Oral administration, Good tissue penetration, Easy mobilization of the iron-chelator complex, Inexpensive, and Non-Toxic.mehr

Produkt

KlappentextIron overload is the accumulation of excess iron in body tissues and Hemochromatosis is a disease that occurs as a result of significant iron overload. Hereditary hemochromatosis is the genetic disease that results from significant iron overload. Acquired iron overload occurs when one obtains excessive amounts of iron from repeated exposure through supplementation, diet, iron shots, blood transfusion. Excess of iron gets deposited in vital organs and tissues such as liver, brain, heart, spleen and bones and leads to problems. The management of iron overload can be divided in to two types mainly.a. Phlebotomy b. Iron Chelationa. Phlebotomy: A phlebotomy is a procedure used to remove blood from a person.b. Iron Chelation: The available treatment for iron Chelation is either having many side effects or is very costly. Patients cannot tolerate the side effects of the daily injections. No ideal chelator exists to treat patients with transfusional iron overload. Still the search for is needed and such a compound can be extrapolated from the clinical requirements: Oral administration, Good tissue penetration, Easy mobilization of the iron-chelator complex, Inexpensive, and Non-Toxic.
Details
ISBN/GTIN978-620-5-52173-1
ProduktartBuch
EinbandartKartoniert, Paperback
Erscheinungsjahr2023
Erscheinungsdatum04.04.2023
Seiten336 Seiten
SpracheEnglisch
Artikel-Nr.16697570
Rubriken
GenreMedizin

Autor

Dr Joban K Modha MD PhD (Ayurved) has done B.A.M.S (in 1995); M.D. (in 1999) PhD. (in 2009) from Gujarat Ayurved University and is Fellow with Iron Overload Diseases Association Florida USA (in 2010). He has certificates like CCC+ from SPIPA in (2013) Leadership Development Program from Indian Institute of Management,Kozikode, India.