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Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

Previously published in hardcover
BuchKartoniert, Paperback
434 Seiten
Englisch
Springer Netherlandserschienen am18.07.20142012
Cell-cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. - How do cadherins and catenins interact to assemble AJs and mediate adhesion? - How do AJs interface with other cellular machinery to couple adhesion with the whole cell? - How do AJs affect cell behaviour and multicellular development?mehr
Verfügbare Formate
BuchKartoniert, Paperback
EUR213,99
BuchGebunden
EUR213,99

Produkt

KlappentextCell-cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. - How do cadherins and catenins interact to assemble AJs and mediate adhesion? - How do AJs interface with other cellular machinery to couple adhesion with the whole cell? - How do AJs affect cell behaviour and multicellular development?
Details
ISBN/GTIN978-94-007-9616-4
ProduktartBuch
EinbandartKartoniert, Paperback
Erscheinungsjahr2014
Erscheinungsdatum18.07.2014
Auflage2012
ReiheSubcellular Biochemistry
Seiten434 Seiten
SpracheEnglisch
Gewicht670 g
IllustrationenVI, 434 p.
Artikel-Nr.15497739
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
1. An introduction to adherens junctions: from molecular mechanisms to tissue development and disease. - Part I: How AJs evolved. - 2. Evolution of the cadherin-catenin complex. - Part II: How cadherins and catenins interact to assemble AJs. - 3. The three-dimensional structure of the cadherin-catenin complex. - 4. Biophysics of cadherin adhesion. - 5. Adherens junction assembly. - Part III: How AJs interface with other cellular machinery. - 6. The cytoskeleton and classical cadherin adhesions. - 7. Immunoglobulin superfamily receptors and adherens junctions. - 8. Signaling from the adherens junction. - 9. Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling. - Part IV: How AJs affect cell behaviour and multicellular development. - 10. Adherens junctions during cell migration. - 11. Adherens junctions and cadherins in Drosophila development. - 12. Adherens junctions in C. elegans embryonic morphogenesis. - 13.Cadherin function during Xenopus gastrulation. - 14. Adherens junctions in mammalian development, homeostasis and disease: lessons from mice. - Part V: How AJs affect tissue homeostasis and disease. - 15. Adherens junctions and stem cells. - 16. Adherens junctions and cancer. - 17. Adherens junctions and pathogens entry.mehr