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Proceedings of the International Conference on Nanomedicine (ICON-2019)

E-BookPDF1 - PDF WatermarkE-Book
164 Seiten
Englisch
Springer International Publishingerschienen am04.10.20191st ed. 2019
This book presents the Proceedings of ICON-2019, an international meeting exclusively dedicated to nanostructured materials in medicinal applications. The conference emphasized the recent advances in multidisciplinary research on processing, morphol¬ogy, structure and properties of nanostructured materials and their applications in vari¬ous medicinal fields. The papers encompass basic studies and applications and address topics of novel issues, difficulties, and breakthroughs in the field of nanomedicine in cancer, tuberculosis, tissue engineering, regenerative medicine etc.mehr
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EUR213,99
E-BookPDF1 - PDF WatermarkE-Book
EUR213,99

Produkt

KlappentextThis book presents the Proceedings of ICON-2019, an international meeting exclusively dedicated to nanostructured materials in medicinal applications. The conference emphasized the recent advances in multidisciplinary research on processing, morphol¬ogy, structure and properties of nanostructured materials and their applications in vari¬ous medicinal fields. The papers encompass basic studies and applications and address topics of novel issues, difficulties, and breakthroughs in the field of nanomedicine in cancer, tuberculosis, tissue engineering, regenerative medicine etc.
Details
Weitere ISBN/GTIN9783030251352
ProduktartE-Book
EinbandartE-Book
FormatPDF
Format Hinweis1 - PDF Watermark
FormatE107
Erscheinungsjahr2019
Erscheinungsdatum04.10.2019
Auflage1st ed. 2019
ReiheSpringer Proceedings in Materials
Seiten164 Seiten
SpracheEnglisch
IllustrationenVI, 164 p. 102 illus., 87 illus. in color.
Artikel-Nr.4896652
Rubriken
Genre9200

Inhalt/Kritik

Inhaltsverzeichnis
1;Contents;6
2;Green Synthesis of Silver Nanoparticles Using Ledebouria Revoluta Bulb Extractand Its Biological Activity;8
2.1;Abstract;8
2.2;1 Introduction;8
2.3;2 Materials and Methods;9
2.3.1;2.1 Preparation of Plant Extract;9
2.3.2;2.2 Synthesis of AgNPs;10
2.3.3;2.3 Characterization of AgNPs;10
2.3.3.1;2.3.1 UV-Vis Spectroscopy;10
2.3.3.2;2.3.2 FTIR Spectroscopy;10
2.3.3.3;2.3.3 XRD Analysis;10
2.3.3.4;2.3.4 HRTEM Analysis;10
2.3.3.5;2.3.5 EDS Analysis;10
2.3.4;2.4 Antibacterial Activity;10
2.3.5;2.5 Cytotoxicity Activity;11
2.3.5.1;2.5.1 Cell Line;11
2.3.5.2;2.5.2 Statistical Analysis;11
2.4;3 Results and Discussion;11
2.4.1;3.1 UV-Vis Spectroscopy;11
2.4.2;3.2 FTIR Spectroscopy;11
2.4.3;3.3 XRD Analysis;12
2.4.4;3.4 HRTEM and EDS;13
2.4.5;3.5 Antibacterial Activity;14
2.4.6;3.6 Cytotoxicity Analysis of A549 Cell Line;15
2.5;4 Conclusion;16
2.6;References;16
3;Precision Medicine: A Personalized Treatment from Your Gene;18
3.1;Abstract;18
3.2;1 Introduction;18
3.3;2 The Role of Artificial Intelligence in Precision Medicine;20
3.4;3 Global Initiatives;21
3.5;4 Future of Precision Medicine;22
3.6;5 Challenges of Precision Medicine;22
3.7;6 Conclusion;23
3.8;References;23
4;Ultrasonic Studies on Molecular Interaction and Their Excess Properties of Ternary Liquid Mixtures of 2-Nitroanisole and 1-Propanol in n-Hexane at Different Temperatures 303, 308 and 313k;25
4.1;Abstract;25
4.2;1 Introduction;26
4.3;2 Materials and Methods;27
4.4;3 Theoretical Aspect;27
4.4.1;3.1 Excess Values;28
4.5;4 Results and Discussion;29
4.6;5 Conclusion;39
4.7;References;39
5;Thermal and Physical Properties of Some Deep Eutectic Solvents;41
5.1;Abstract;41
5.2;1 Introduction;41
5.3;2 Experimental;42
5.3.1;2.1 Materials;42
5.3.2;2.2 Preparation of DESs;42
5.3.3;2.3 Characterization of DES;42
5.4;3 Results and Discussion;42
5.4.1;3.1 Conductivity;43
5.4.2;3.2 Density;43
5.4.3;3.3 Viscosity;43
5.4.4;3.4 The PH;44
5.4.5;3.5 Thermal Decomposition Temperature;44
5.4.6;3.6 FTIR Spectrum of Citric Acid-Glycine;45
5.4.7;3.7 FTIR Spectrum of Malonic Acid-Glycine;46
5.4.8;3.8 FTIR Spectrum of Ethylene Glycol-Tartaric Acid;46
5.5;4 Conclusions;47
5.6;Acknowledgement;47
5.7;References;47
6;Apoptotic Activity in Cervical Cancer HeLa Cell Lines Treated with Chitosan Nanoconjugated Drug Doxorubicin - as Nanocarrier for Drug Delivery;49
6.1;Abstract;49
6.2;1 Introduction;49
6.3;2 Materials and Methods;50
6.3.1;2.1 Synthesis of Chitosan Nanoconjugated Drug;50
6.3.2;2.2 Characterization of Nanoparticles Using UV Visible Spectrophotometer;51
6.3.3;2.3 Zeta Potential;51
6.3.4;2.4 SEM & HRSEM Analysis (Scanning Electron and High Resolution Scanning Electron Microscope);51
6.3.5;2.5 Phytochemical Analysis the Green Extracts of the Plants Tested;51
6.3.6;2.6 In Vitro Cytotoxicity and Anti Cancer Activity of the Gold Nanoparticles;52
6.3.7;2.7 Apoptotic Gene Expression - Western Blotting;52
6.4;3 Results and Discussion;52
6.4.1;3.1 Synthesis of Chitosan Nanoconjugated Drug;52
6.4.2;3.2 Characterization - UV-Visible Spectrometer Analysis;53
6.4.3;3.3 Zeta Potential Analysis;53
6.4.4;3.4 SEM & HRSEM-Scanning Electron Microscope and High Resolution Scanning Electron Microscope Images;55
6.4.5;3.5 In Vitro Cytotoxicity in Vero Cell Lines;55
6.4.6;3.6 In Vitro Anti Cancer Activity in Cervical Cancer Hela Cell Lines;57
6.4.7;3.7 Protein Expression - Western Blotting;57
6.5;4 Summary;58
6.6;5 Conclusion;58
6.7;Conflict of Interests;59
6.8;References;59
7;One Step Synthesis of Reduced and Moringa oleifera Treated Graphene Oxide: Characterization and Antibacterial Studies;61
7.1;Abstract;61
7.2;1 Introduction;61
7.3;2 Materials and Methods;62
7.3.1;2.1 Synthesis of reduced Graphene Oxide (rGO);62
7.3.2;2.2 Extract Preparation of Moringa oleifera;63
7.3.3;2.3 Preparation of Moringa oleifera Treated rGO Composite;63
7.3.4;2.4 Antibacterial Activity;63
7.3.5;2.5 Characterisation Techniques;63
7.4;3 Results and Discussion;63
7.4.1;3.1 FTIR Analysis;63
7.4.2;3.2 Raman Spectroscopic Studies;64
7.4.3;3.3 XRD Analysis;65
7.4.4;3.4 Morphological Analysis;66
7.4.5;3.5 Antibacterial Studies;68
7.5;4 Conclusion;68
7.6;References;68
8;Encapsulation of Amphotericin B into Quercetin Based Silver Nanoparticles: Preparation, Characterization and Preliminary Investigation of Antiparasitic Activity;70
8.1;Abstract;70
8.2;1 Introduction;70
8.3;2 Materials and Methods;71
8.3.1;2.1 Materials;71
8.3.2;2.2 Preparation of AmB-AgNP Nanoformulations;71
8.3.3;2.3 Characterization of AmB-AgNP Nanoformualtion;72
8.3.3.1;2.3.1 UV/Visible Spectrum Analysis;72
8.3.3.2;2.3.2 FTIR Analysis;72
8.3.3.3;2.3.3 Scanning Electron Microscopic Observation of AmB-AgNP Nanoformualtion;72
8.3.3.4;2.3.4 Antifungal Activity of AmB-AgNPs Nanoformulation;72
8.3.3.5;2.3.5 In Vitro Cytotoxicity of AmB-AgNP Nanoformulation Against L. Donovani (Dd8 Strain) Parasites by MTT Assay;72
8.4;3 Results and Discussion;72
8.4.1;3.1 UV/VIS Analysis;72
8.4.2;3.2 Morphological Analysis of AmB-AgNP;73
8.4.3;3.3 FTIR Analysis;73
8.4.4;3.4 Antifungal Activity of AmB-AgNP Nanoformualtion Against Verticillium Dahliae;74
8.4.5;3.5 Efficacy of Nanoformulation (AgNPs with AmB Drug) on L. Donovani Promastigote by MTT Assay;75
8.5;4 Conclusion;77
8.6;References;77
9;Dual Delivery of Antibiotic and Antiresorptive Drugs by Hydroxyapatite-Chitosan Composite Nanocarrier for the Treatment of Osteomyelitis;79
9.1;Abstract;79
9.2;1 Introduction;79
9.3;2 Materials and Methods;81
9.3.1;2.1 Synthesis of SA Loaded HA NPs;81
9.3.2;2.2 Chitosan Coating on HA NPs and SA-HA NPs;81
9.3.3;2.3 GEN Loaded CH-SA-HA NPs;82
9.3.4;2.4 In Vitro Drug Release Studies;82
9.3.5;2.5 Antibacterial Activity Studies;82
9.3.5.1;2.5.1 Broth Microdilution Assay;82
9.3.5.2;2.5.2 Agar Diffusion Assay;83
9.4;3 Results and Discussion;83
9.4.1;3.1 Characterization of NPs;83
9.4.2;3.2 Coating Efficiency in HA NPs;86
9.4.3;3.3 Drug Loading Efficiency in HA NPs;86
9.4.4;3.4 In Vitro Drug Release;87
9.4.5;3.5 Antibacterial Studies;87
9.5;4 Conclusions;89
9.6;Conflict of Interest;90
9.7;References;90
10;The Impact of Gold Nanoparticles with Low Energy Irradiation Treatment on Temperature Induction and Cell Viability of Breast Cancer Cell;93
10.1;Abstract;93
10.2;1 Introduction;94
10.3;2 Experimental;95
10.3.1;2.1 Materials and Reagent;95
10.3.2;2.2 Synthesis of AuNPs;95
10.3.3;2.3 Cell Culture Procedure;96
10.3.4;2.4 In-Vitro Cell Cytotoxicity Study After Treating with AuNPs and a LED Irradiation;96
10.3.5;2.5 Characterization Techniques;97
10.4;3 Results and Discussion;97
10.4.1;3.1 Characterization of AuNPs;97
10.4.2;3.2 Cell Viability Test After Treating with AuNPs and Exposing to a LED Irradiation;98
10.5;4 Conclusion;99
10.6;References;99
11;Green Synthesis of Silver Nanoparticles from De-oiled Rhizomes of Curcuma longa L. and Its Biomedical Potential;101
11.1;Abstract;101
11.2;1 Introduction;101
11.3;2 Materials and Methods;103
11.3.1;2.1 Materials;103
11.3.2;2.2 Preparation of Extracts;104
11.3.3;2.3 Synthesis of AgNPs;104
11.4;3 Characterization of AgNPs;104
11.5;4 Antimicrobial Activity;105
11.6;5 Anticancer Study;105
11.6.1;5.1 Preparation of Cell Suspension;105
11.6.2;5.2 Seeding of Cells;105
11.6.3;5.3 Cytotoxicity Assay;105
11.7;6 Results and Discussion;106
11.7.1;6.1 Characterisation of Silver Nanoparticles;106
11.7.2;6.2 Biomedical Potential;109
11.8;7 Conclusion;112
11.9;References;112
12;In-Vitro Wound Healing and Release Kinetics of ?-Cyclodextrin Encapsulated Curcumin Loaded Carrageenan Hydrogel Film: An Efficient Wound Dressing Material;114
12.1;Abstract;114
12.2;1 Introduction;114
12.3;2 Materials;117
12.4;3 Methods;117
12.4.1;3.1 Preparation and Optimization of Gel Films;117
12.4.2;3.2 Encapsulation/Preparation of ?-Cyclodextrin Curcumin Nano Micelle;117
12.4.3;3.3 Preparation of NMC-Hydrogels;118
12.4.4;3.4 Encapsulation Efficiency;118
12.4.5;3.5 Particle Size Analysis and Zeta Potential;118
12.4.6;3.6 Release Studies;118
12.4.7;3.7 Swelling Studies;118
12.4.8;3.8 Free Radical Scavenging Activity;118
12.5;4 Results and Discussion;119
12.5.1;4.1 FT-IR;119
12.5.2;4.2 Texture Studies;120
12.5.3;4.3 Film Formation;120
12.5.4;4.4 Drug Encapsulation Efficiency;120
12.5.5;4.5 Particle Size;121
12.5.6;4.6 Zeta Potential;121
12.5.7;4.7 Release Kinetics;122
12.5.8;4.8 Swelling Studies;123
12.5.9;4.9 Free Radical Scavenging Activity;123
12.6;5 Conclusion;124
12.7;References;125
13;Phytosynthesis of Silver Nanoparticles Using Rhynchosia heynei Wight & Arn Leaf Extract: Characterization and in Vitro Assessment of Antimicrobial, Antioxidant and Anticancer Activities;127
13.1;Abstract;127
13.2;1 Introduction;128
13.3;2 Materials and Methods;130
13.3.1;2.1 Chemicals;130
13.3.2;2.2 Collection of Plant Material;130
13.3.3;2.3 Phytochemical Screening, Estimation of Total Phenolic and Flavonoid Contents from Aqueous Leaf Extract of R. heynei (RHLE);131
13.3.4;2.4 Preparation of Plant Extract of RHLE and Phytosynthesis of RH-AgNPs;131
13.3.5;2.5 Characterization of RH-AgNPs;132
13.3.6;2.6 In Vitro Biological Effects;132
13.3.6.1;2.6.1 In Vitro Assessment of Antimicrobial Property of RH-AgNPs;132
13.3.6.2;2.6.2 In Vitro Assessment of Antioxidant Property Assay of RH-AgNPs;132
13.3.6.3;2.6.3 DPPH Radical Scavenging Assay;132
13.3.6.4;2.6.4 H2O2 Radical Scavenging Assay;133
13.3.6.5;2.6.5 In Vitro Assessment of Anticancer Activity Assay of RH-AgNPs;133
13.4;3 Results and Discussion;133
13.4.1;3.1 Phytosynthesis of RH-AgNPs;134
13.4.2;3.2 FTIR Analysis of RH-AgNPs;134
13.4.3;3.3 XRD and EDX Analysis of RH-AgNPs;135
13.4.4;3.4 TEM Study and SAED Pattern of RH-AgNPs;136
13.4.5;3.5 DLS Analysis of RH-AgNPs;138
13.4.6;3.6 In Vitro Biological Effects;138
13.4.6.1;3.6.1 In Vitro Assessment of Antimicrobial Activity Assay of RH-AgNPs;138
13.4.6.2;3.6.2 In Vitro Assessment of Antioxidant Activity Assay of RH-AgNPs;141
13.4.6.3;3.6.3 In Vitro Assessment of Anticancer Activity Assay of RH-AgNPs;142
13.5;4 Conclusion;143
13.6;Acknowledgements;143
13.7;Compliance with Ethical Standards;143
13.8;References;144
14;Acoustical and Excess Properties on Ternary Liquid Mixtures of Ortho Methoxy Phenol, 1 Butanol and n-Hexane at Different Temperatures;148
14.1;Abstract;148
14.2;1 Introduction;148
14.3;2 Materials and Methods;149
14.3.1;2.1 Theory and Calculations;150
14.4;3 Results and Discussions;151
14.5;4 Conclusions;159
14.6;References;159
15;A Facile Route for the Fabrication of Nanocompositie by Effective Impregnation Through the Biopolymer Matrix and Its Characterisation;160
15.1;Abstract;160
15.2;1 Introduction;160
15.3;2 Materials and Methods;162
15.4;3 Results and Discussion;162
15.4.1;3.1 XRD;162
15.4.2;3.2 SEM;162
15.4.3;3.3 TEM;163
15.4.4;3.4 FTIR;164
15.4.5;3.5 UV-Vis;165
15.4.6;3.6 AFM;165
15.5;4 Conclusion;166
15.6;References;167
16;Author Index;169mehr

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