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Models of Calcium Signalling

BuchGebunden
436 Seiten
Englisch
Springererschienen am15.06.20161st ed. 2016
This book discusses the ways in which mathematical, computational, and modelling methods can be used to help understand the dynamics of intracellular calcium. The concentration of free intracellular calcium is vital for controlling a wide range of cellular processes, and is thus of great physiological importance. However, because of the complex ways in which the calcium concentration varies, it is also of great mathematical interest.This book presents the general modelling theory as well as a large number of specific case examples, to show how mathematical modelling can interact with experimental approaches, in an interdisciplinary and multifaceted approach to the study of an important physiological control mechanism.Geneviève Dupont is FNRS Research Director at the Unit of Theoretical Chronobiology of the Université Libre de Bruxelles; Martin Falcke is head of the Mathematical Cell Physiology group at the Max Delbrück Center for Molecular Medicine, Berlin; Vivien Kirk is an Associate Professor in the Department of Mathematics at the University of Auckland, New Zealand; James Sneyd is a Professor in the Department of Mathematics at The University of Auckland, New Zealand.mehr
Verfügbare Formate
BuchGebunden
EUR90,94
BuchKartoniert, Paperback
EUR64,19
E-BookPDF1 - PDF WatermarkE-Book
EUR64,19

Produkt

KlappentextThis book discusses the ways in which mathematical, computational, and modelling methods can be used to help understand the dynamics of intracellular calcium. The concentration of free intracellular calcium is vital for controlling a wide range of cellular processes, and is thus of great physiological importance. However, because of the complex ways in which the calcium concentration varies, it is also of great mathematical interest.This book presents the general modelling theory as well as a large number of specific case examples, to show how mathematical modelling can interact with experimental approaches, in an interdisciplinary and multifaceted approach to the study of an important physiological control mechanism.Geneviève Dupont is FNRS Research Director at the Unit of Theoretical Chronobiology of the Université Libre de Bruxelles; Martin Falcke is head of the Mathematical Cell Physiology group at the Max Delbrück Center for Molecular Medicine, Berlin; Vivien Kirk is an Associate Professor in the Department of Mathematics at the University of Auckland, New Zealand; James Sneyd is a Professor in the Department of Mathematics at The University of Auckland, New Zealand.
Zusammenfassung
Includes the description of calcium signaling in different cell types

Provides appropriate descriptions for each channel involved in intracellular calcium dynamics

Provides realistic, up-to-date examples to teach bifurcation analysis
Details
ISBN/GTIN978-3-319-29645-6
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2016
Erscheinungsdatum15.06.2016
Auflage1st ed. 2016
Seiten436 Seiten
SpracheEnglisch
Gewicht856 g
IllustrationenXXIII, 436 p. 152 illus., 38 illus. in color.
Artikel-Nr.36835756

Inhalt/Kritik

Inhaltsverzeichnis
Some Background Physiology.- The Calcium Toolbox.- Basic Modeling Principles: Deterministic Models.- Hierarchical and Stochastic Modeling.- Nonlinear Dynamics of Calcium.- Nonexcitable Cells.- Muscle.- Neurons and Other Excitable Cells.mehr
Kritik
"This book is entirely focused on the modelling aspects: how quantitative models of calcium signalling are constructed, 'and how they can help build bridges between seemingly unrelated observations' ... . The book is intended for people who are familiar with the basic theory of differential equations. ... A selected list of literature for further productive reading on different levels of knowledge is given." (Luisa Consiglieri, zbMATH 1350.92002, 2017)mehr

Schlagworte

Autor

Geneviève Dupont is Senior Research Associate at Universite Libre de Bruxelles. Martin Falcke is head of the Mathematical Cell Physiology group at the Max Delbruck Center for Molecular Medicine.
Vivien Kirk is Associate Professor of Mathematics at the University of Auckland.
James Sneyd is Professor of Mathematics at the University of Auckland.