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Toxicology of Nanomaterials

E-BookEPUB2 - DRM Adobe / EPUBE-Book
407 Seiten
Englisch
Wiley-VCHerschienen am08.09.20161. Auflage
This book provides the reader with a comprehensive view of analytical methods for nanotoxicology studies. After an introduction to nanomaterials and toxicological studies, the book discusses various characterization methods of nanomaterials and continues with the detection of nanoparticles in vivo as well as in vitro. A variety of techniques in molecular toxicology of nanomaterials is presented, followed by a detailed explanation of interaction between nanoparticles and biomacromolecules, including the structure-toxicity relationships of nanomaterials. Finally, the book concludes with the advantages and challenges of the analytical methods for nanotoxicology.

Zhiyong Zhang holds a PhD in radiochemistry from Beijing University, China. He is a professor and a scientific leader in environment health and safety at the Chinese Academy of Sciences in the Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety. His current research interests are in coordination chemistry, bioinorganic chemistry, and environmental chemistry of rare earth elements, as well as toxicology and ecotoxicology of nanomaterials.

Weiyue Feng graduated from Fudan University of Applied Chemistry, China, in 1989 and received her PhD from the Institute of High Energy Physics, Chinese Academy of Sciences, in 1998. She is currently professor of inorganic chemistry and biological chemistry. Her primary fields of research include chemical biology, metallomics and metalloproteins as well as biological and toxicological studies of nanomaterials.

Yuliang Zhao is Professor in Chemistry and Physics. He moved to Chinese Academy of Sciences from RIKEN, Japan, as a Hundred Elite Professor in 2001. His research is mainly focused on the biomedical effects of nanostructures and nanoscale materials, including the biomedical functions of nanomaterials, the toxicological effects of nanomaterials and establishing standard procedures for safety assessment of nanoproducts, surface chemistry of nanoparticles and their novel properties, and molecular dynamics using theoretical simulation of the dynamic processes of the interplay between nanosystems and biosystems.
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Verfügbare Formate
E-BookPDF2 - DRM Adobe / Adobe Ebook ReaderE-Book
EUR151,99
E-BookEPUB2 - DRM Adobe / EPUBE-Book
EUR151,99

Produkt

KlappentextThis book provides the reader with a comprehensive view of analytical methods for nanotoxicology studies. After an introduction to nanomaterials and toxicological studies, the book discusses various characterization methods of nanomaterials and continues with the detection of nanoparticles in vivo as well as in vitro. A variety of techniques in molecular toxicology of nanomaterials is presented, followed by a detailed explanation of interaction between nanoparticles and biomacromolecules, including the structure-toxicity relationships of nanomaterials. Finally, the book concludes with the advantages and challenges of the analytical methods for nanotoxicology.

Zhiyong Zhang holds a PhD in radiochemistry from Beijing University, China. He is a professor and a scientific leader in environment health and safety at the Chinese Academy of Sciences in the Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety. His current research interests are in coordination chemistry, bioinorganic chemistry, and environmental chemistry of rare earth elements, as well as toxicology and ecotoxicology of nanomaterials.

Weiyue Feng graduated from Fudan University of Applied Chemistry, China, in 1989 and received her PhD from the Institute of High Energy Physics, Chinese Academy of Sciences, in 1998. She is currently professor of inorganic chemistry and biological chemistry. Her primary fields of research include chemical biology, metallomics and metalloproteins as well as biological and toxicological studies of nanomaterials.

Yuliang Zhao is Professor in Chemistry and Physics. He moved to Chinese Academy of Sciences from RIKEN, Japan, as a Hundred Elite Professor in 2001. His research is mainly focused on the biomedical effects of nanostructures and nanoscale materials, including the biomedical functions of nanomaterials, the toxicological effects of nanomaterials and establishing standard procedures for safety assessment of nanoproducts, surface chemistry of nanoparticles and their novel properties, and molecular dynamics using theoretical simulation of the dynamic processes of the interplay between nanosystems and biosystems.
Details
Weitere ISBN/GTIN9783527689156
ProduktartE-Book
EinbandartE-Book
FormatEPUB
Format Hinweis2 - DRM Adobe / EPUB
FormatFormat mit automatischem Seitenumbruch (reflowable)
Verlag
Erscheinungsjahr2016
Erscheinungsdatum08.09.2016
Auflage1. Auflage
Seiten407 Seiten
SpracheEnglisch
Dateigrösse15179 Kbytes
Artikel-Nr.3266941
Rubriken
Genre9201

Inhalt/Kritik

Leseprobe
Abbreviations
2-DGE two-dimensional gel electrophoresis ADME absorption, distribution, metabolism, and excretion AES auger electron spectroscopy AFM atomic force microscope AMBER assisted model building with energy refinement AMs alveolar macrophages AMU atomic mass unit ARDRA amplified ribosomal DNA restriction analysis BALF bronchoalveolar lavage fluid BBB blood-brain barrier BFG bovine fibrinogen BO bond order BSA bovine serum albumin C2 molecule of two C atoms CAT catalase CD circular dichroism CE capillary electrophoresis CE-MS capillary electrophoresis-mass spectrometry CHARMM chemistry Harvard macromolecular mechanics CMAP cross-term map CNS central nervous system CTAB cetyltrimethylammonium bromide CT-SPECT computed tomography coregistered with single-photon emission computerized tomography Cyt c cytochrome c DCFH-DA dichlorodihydrofluorescein diacetate DCS differential centrifugal sedimentation DFT density function theory DGGE denaturing gradient gel electrophoresis DLS dynamic light scattering DMEM Dulbecco's modified eagle's medium DOTA 1,4,7,10-tetraazacyclododecane-tetraacetic acid dsDNA double-strand DNA EDX or EDS energy-dispersive X-ray spectroscopy EE electron equilibration EELS electron energy-loss spectroscopy EGP effective group potentials ELISA enzyme-linked immunosorbent assay ENM engineered nanomaterial EPR electron paramagnetic resonance ESCA electron spectroscopy for chemical analysis ESEM environmental scanning electronic microscopy ESI-MS electrospray ionization-mass spectrometry EXAFS extended X-ray absorption fine structure FBS fetal bovine serum FCM flow cytometry FFF field flow fractionation FISH fluorescence in situ hybridization FTIR Fourier-transform infrared spectroscopy GC gas chromatography GC-MS gas chromatography-mass spectrometry GE gel electrophoresis GGA generalized gradient approximation GHO generalized hybrid orbital GO graphene oxide GROMOS Groningen molecular simulation GPx glutathione peroxidase HCS high-content screening HDC hydrodynamic chromatography HPLC high-performance liquid chromatography HPRT hypoxanthine-guanine phosphoribosyltransferase HSA human serum albumin ICP-MS inductively coupled plasma-mass spectrometry ICP-OES inductively coupled plasma-optical emission spectrometer Ig gamma globulin IgG immunoglobulin G IR infrared spectroscopy IRMS isotope ratio mass spectrometry ITC isothermal titration calorimetry LA-ICP-MS laser ablation-inductively coupled plasma-mass spectrometry LC-MS liquid chromatography-mass spectroscopy LCSM laser confocal scanning microscopy LDH lactate dehydrogenase LEIS low-energy ion scattering LSCF local self-consistent field LSDA local spin density approximation MALDI-TOF-MS matrix-assisted laser desorption/ionization time-of-flight mass spectrometry MD molecular dynamics MDA malondialdehyde MFM multiphoton fluorescence microscope MMP-9 matrix metalloproteinases-9 MN micronucleus MRI magnetic resonance imaging MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MWCNTs multiwalled carbon nanotubes NAA neutron activation analysis NADH nicotinamide adenine dinucleotide NADPH nicotinamide adenine dinucleotide phosphate NanoXRF SRXRF with the nanosized spatial resolution NEGF nonequilibrium Green's function NM nanomaterial NMR nuclear magnetic resonance NOM natural organic matters NOTA 1,4,7-triazacyclononane-1,4,7-triacetic acid NP nanoparticle OPLS-AA optimized potentials for liquid simulations-all atom PAA poly(acrylic acid) PC protein corona PCR-DGGE polymerase chain reaction-denaturing gradient gel electrophoresis PET positron emission tomography PLFA phospholipid fatty acid PME particle mesh Ewald PMF potential of mean force PVP polyvinyl pyrrolidone QDs quantum dots QEq Q Equilibration QM/MM quantum mechanics/molecular mechanics qPCR quantitative polymerase chain reaction REMD replica-exchange molecular dynamics RES reticuloendothelial systems REST replica exchange with solvent tempering rGO reduced graphene oxide RMSD root mean square deviation RMSF root mean square fluctuation ROS reactive oxygen species RT-PCR reverse transcription polymerase chain reaction SAXS small-angle X-ray scattering SBO sum of Ï-bond order SCE sister chromatid exchange SCGE single-cell gel electrophoresis assay SDS-PAGE sodium dodecylsulphate-polyacrylamide gel electrophoresis SEC size-exclusion chromatography SEM scanning electron microscope SERS surface-enhanced Raman spectroscopy SIEMN inhalation exposure for manufactured...
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