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Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions

E-BookPDF1 - PDF WatermarkE-Book
326 Seiten
Englisch
Springer Nature Switzerlanderschienen am05.03.20184th ed. 2018
The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes - 'Mechanisms and Models of Drug Interactions' and 'Antimicrobial Drug Interactions'.

This volume, 'Mechanisms and Models of Drug Interactions,' delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation.  The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.



Manjunath P. Pai, College of Pharmacy, University of Michigan, Ann Arbor, MI 

Jennifer J. Kiser, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 

Paul O. Gubbins, School of Pharmacy, University of Missouri-Kansas City, Springfield, MO
Keith A. Rodvold, University of Illinois, College of Pharmacy and Medicine, Chicago, IL
mehr
Verfügbare Formate
BuchGebunden
EUR64,19
E-BookPDF1 - PDF WatermarkE-Book
EUR64,19

Produkt

KlappentextThe 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes - 'Mechanisms and Models of Drug Interactions' and 'Antimicrobial Drug Interactions'.

This volume, 'Mechanisms and Models of Drug Interactions,' delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation.  The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.



Manjunath P. Pai, College of Pharmacy, University of Michigan, Ann Arbor, MI 

Jennifer J. Kiser, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 

Paul O. Gubbins, School of Pharmacy, University of Missouri-Kansas City, Springfield, MO
Keith A. Rodvold, University of Illinois, College of Pharmacy and Medicine, Chicago, IL
Details
Weitere ISBN/GTIN9783319724225
ProduktartE-Book
EinbandartE-Book
FormatPDF
Format Hinweis1 - PDF Watermark
FormatE107
Erscheinungsjahr2018
Erscheinungsdatum05.03.2018
Auflage4th ed. 2018
Seiten326 Seiten
SpracheEnglisch
Dateigrösse4381 Kbytes
IllustrationenXVI, 326 p. 8 illus., 5 illus. in color.
Artikel-Nr.3380159
Rubriken
Genre9200

Inhalt/Kritik

Inhaltsverzeichnis
Introduction to Drug-Drug Interactions.- Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion.- Mechanisms of Drug Interactions II: Transport Proteins.- Drug-Food Interactions.- Drug-Cytokine Interactions.- Interactions between Herbs and Antiinfective Medications.- In vitro Modeling of Drug-Drug Interactions.- Probe Cocktail Studies.- Design and Data Analysis in Drug Interaction Studies.mehr

Autor