Mouse Models of Human Blood Cancers

Basic Research and Pre-clinical Applications

von

Herausgegeben:Li, Shaoguang

BuchGebunden

293 Seiten

Englisch

Springererschienen am19.08.2008

In this book, Dr. Li and his author team plan to emphasize why mouse models are useful in vivo systems for understanding disease mechanisms and developing therapeutic strategies in blood cancers.mehr

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KlappentextIn this book, Dr. Li and his author team plan to emphasize why mouse models are useful in vivo systems for understanding disease mechanisms and developing therapeutic strategies in blood cancers.

ZusammenfassungDr. Li and his Jackson Laboratory team emphasize why mouse models are useful in vivo systems for understanding disease mechanisms and developing therapeutic strategies in blood cancers. The Jackson Laboratory is the world's largest mouse genetics institution.

Details

ISBN/GTIN978-0-387-69130-5

ProduktartBuch

EinbandartGebunden

Verlag

Springer

Erscheinungsjahr2008

Erscheinungsdatum19.08.2008

Seiten293 Seiten

SpracheEnglisch

Gewicht590 g

IllustrationenX, 293 p.

Artikel-Nr.10904671

Rubriken

GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis

Chapter 1 Mouse models of myeloproliferative disease associated with mutant JAK2 tyrosine kinase: insights into pathophysiology and therapy Richard A. Van Etten Chapter 2 Genetic modeling of human blood cancers in mice Yiguo Hu and Shaoguang Li Chapter 3 Murine Models of Hematopoietic Disease: Pathologic Analysis and Characterization Benjamin H Lee and Jeffery L. Kutok Chapter 4 Mechanisms of DNA double strand break repair in hematopoietic homeostasis and oncogenesis Sarah A. Maas, Lura Brianna Caddle, and Kevin D. Mills Chapter 5 Modeling human leukemia using immune-compromised mice F Ishikawa, Y Saito, and LD Shultz Chapter 6 Dietary Restriction: A model system probing the cell fate decision between cancer and senescence Robin P. Ertl and David E. Harrison Chapter 7 Modeling human Philadelphia chromosome-positive leukemia in mice Shaoguang Li Chapter 8 Mouse Models of Human Mature B Cell and Plasma Cell Neoplasms Siegfried Janz, Herbert C. Morse III, and Michael A. Teitell Chapter 9 Genetic and Virological Predisposition to Pre-B Lymphomagenesis in SL/Kh Hiroshi Hiai Chapter 10 Animal cancer models in anticancer drug discovery and development Francis Lee and Roberto Weinmann Bristol-Myers Squibb Oncology, Princeton, New Jersey, USA Chapter 11 DGL Global Strategies in DNA Microarray Gene Expression Analysis and Data Mining forHuman Blood Cancers Dongguang Limehr