Hugendubel.info - Die B2B Online-Buchhandlung 

Merkliste
Die Merkliste ist leer.
Bitte warten - die Druckansicht der Seite wird vorbereitet.
Der Druckdialog öffnet sich, sobald die Seite vollständig geladen wurde.
Sollte die Druckvorschau unvollständig sein, bitte schliessen und "Erneut drucken" wählen.

The Centrosome

Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease
BuchGebunden
398 Seiten
Englisch
Springererschienen am14.07.2012
The Centrosome: Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease includes chapters on classic and modern aspects of centrosome research to cover topics of current interest that have not been covered in depth in most books on the market so far.mehr
Verfügbare Formate
BuchGebunden
EUR160,49
BuchKartoniert, Paperback
EUR117,69
E-BookPDF1 - PDF WatermarkE-Book
EUR106,99

Produkt

KlappentextThe Centrosome: Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease includes chapters on classic and modern aspects of centrosome research to cover topics of current interest that have not been covered in depth in most books on the market so far.
ZusammenfassungThis book surveys classic and modern aspects of centrosome research, expanding on previous topics and offering exciting new aspects of centrosome research focused on primary cilia and their dysfunctions that are implicated in numerous diseases.
Details
ISBN/GTIN978-1-62703-034-2
ProduktartBuch
EinbandartGebunden
Verlag
Erscheinungsjahr2012
Erscheinungsdatum14.07.2012
Seiten398 Seiten
SpracheEnglisch
Gewicht725 g
IllustrationenXIV, 398 p.
Artikel-Nr.17875854

Inhalt/Kritik

Inhaltsverzeichnis
Centriole Duplication and Inheritance in Drosophila melanogaster.- Sperm Centrioles and their Dual Role in Flagellogenesis and Cell Cycle of the Zygote Structure, Function and Pathology.- Centrosomal Functions and Dysfunctions in Cat Spermatozoa.- Nuclear-Centrosome Relationships During Fertilization, Cell Division, Embryo Development, and in Somatic Cell Nuclear Transfer (SCNT) Embryos.- Human Centrosomal Dynamics During Gametogenesis, Fertilization and Embryogenesis and its Impact on Fertility: Ultrastructure.- Asymmetric Centrosome Behavior in Stem Cell Divisions.- Functional Associations Between the Golgi Apparatus and the Centrosome in Mammalian Cells.- Many Pathways to Destruction: The Centrosome and its Control by and Role in Regulated Proteolysis.- Regulation of the Centrosome Cycle by Protein Degradation.- Molecular Links Between Centrosome Duplication and Other Cell Cycle Associated Events.- Regulation of Centrosomes by Cyclin-Dependent Kinases.- Disruption of Centrosome Duplication Control and Induction of Mitotic Instability by the High-Risk Human Papillomavirus Oncoproteins E6 and E7.- Centrosomes, DNA Damage and Aneuploidy.- Centrosome Regulation and Breast Cancer.- The Role of Centrosomes in Multiple Myeloma.- Centrosomal Amplification and Related Abnormalities Induced by Nucleoside Analogs.- Mechanisms and Consequences of Centrosome Clustering in Cancer Cells.- Re-Evaluation of the Neuronal Centrosome as a Generator of Microtubules for Axons and Dendrites.- Centrosomes and Cell Division in Apicomplexa.- The Centrosome Life Story in Xenopus leavis.- Role of the MTOC in T cell Effector Functions.- Thoughts on Progress in the Centrosome Field.mehr
Kritik
From the reviews:"This book is a perfect introduction to the field of centrosome research as well as an excellent reference for those interested in the functions of the centrosome in the cell. ... The chapters are written by experts in their respective areas, which results in a high level of knowledge and detail. This is an excellent introduction for investigators entering the field of centrosome research as well as a good reference for researchers already in the field." (Ruben Mestril, Doody's Book Reviews, June, 2013)
mehr

Autor


Heide Schatten is Professor at the University of Missouri, Columbia, USA.  She is a cell biologist with research focused on cytoskeletal regulation in various cell systems and on cytoskeletal dysfunctions of the centrosome-microtubule complex that play a role in disease such as cancer and in disorders such as infertility and other reproductive disorders. 

She received her M.S. and Ph.D. degrees from the Karl-Ruprecht University in Heidelberg, Germany, and performed her Ph.D. research studies at the German Cancer Research Center in Heidelberg. She performed pre-and postdoctoral studies with Professor Daniel Mazia at the University of California, Berkeley, who introduced her to the fascinating field of centrosome biology and generated unlimited enthusiasm for centrosome research that she pursued in collaborations with Daniel Mazia and numerous colleagues in cell, molecular, and reproductive biology in the USA, Europe, China, and Latin America. She has given numerous presentations in these and other countries. Her studies also included collaborations with NASA scientists and experiments aboard the Space Shuttle Endeavour to examine the effects of spaceflight on centrosome-cytoskeletal regulation during development.

Her publications include cellular and molecular biology, cancer biology, reproductive biology, microbiology, space biology, and advanced imaging methods including novel imaging techniques that she employed in close collaborations with Professor Hans Ris at the University of Wisconsin-Madison to analyze cellular structures in their three-dimensional network.
She is a member of the American Society for Cell Biology, American Association for the Advancement of Science, and Microscopy Society of America. She has received numerous awards including grant awards from NASA, NIH, and NSF.  She has published over 190 papers, 7 book chapters and edited several special topics journal issues and 8 books with several more inprogress.