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Cell Culture Engineering and Technology

In appreciation to Professor Mohamed Al-Rubeai
BuchKartoniert, Paperback
550 Seiten
Englisch
Springererschienen am22.02.20231st ed. 2021
It comprises contributions of active researchers in the field of cell culture development for the production of recombinant proteins, cell line development, cell therapy and gene therapy, with consideration of media development, process scale-up, reactor design, monitoring and control and model-assisted strategies for process design.mehr
Verfügbare Formate
BuchGebunden
EUR160,49
BuchKartoniert, Paperback
EUR117,69

Produkt

KlappentextIt comprises contributions of active researchers in the field of cell culture development for the production of recombinant proteins, cell line development, cell therapy and gene therapy, with consideration of media development, process scale-up, reactor design, monitoring and control and model-assisted strategies for process design.
Details
ISBN/GTIN978-3-030-79873-4
ProduktartBuch
EinbandartKartoniert, Paperback
Verlag
Erscheinungsjahr2023
Erscheinungsdatum22.02.2023
Auflage1st ed. 2021
ReiheCell Engineering
Seiten550 Seiten
SpracheEnglisch
IllustrationenX, 550 p. 1 illus.
Artikel-Nr.51988305
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
Biopharmaceuticals Produced from Cultivated Mammalian Cells.- Remote Control of Mammalian Therapeutic Designer Cells.- Next generation cell engineering using microRNAs.- An Omic´s data-driven approach towards engineering mammalian cell factories and bioprocesses for biopharmaceutical production.- Redesigning spent media from cell culture bioprocess to feed new bacterial fermentations.- Monoclonal antibody glycoengineering for biopharmaceutical quality assurance.- Next-generation cell engineering platform for improving recombinant protein production in mammalian cells.- Manufacturing human pluripotent stem cells and differentiated progenitors.- Biomanufacturing of Mesenchymal Stromal Cell for Therapeutic Applications.- Process Design for hMSC Products in Stirred Tank Bioreactors.- Bio-production of Adeno-associated virus for gene therapy.- Scale-up (and scale-down) of CHO cell culture, with a focus on how to adjust the various culture parameters/setpoints across different systems from lab-scale to manufacturing-scale.- Intensified and Continuous mAb Production with Single-Use Systems.- Mathematical modelling of cell culture processes.- Model-assisted design concepts for mammalian cell culture processes.- Bioprocess monitoring and control.- Industrial Monitoring of Cell Culture.mehr

Schlagworte

Autor

Prof. Dr.-Ing. Ralf Pörtner is a senior research associate and group leader at Technical University Hamburg, Institute of Bioprocess and Biosystems Engineering and Honorary Professor at TH Mittelhessen University of Applied Sciences, Giessen. The main research interests of Prof. Pörtner are development and optimization of bioreactor techniques and process strategies, in particular for cell cultures and microbial reactions, including model-based control concepts, and tissue engineering. He has in total published 135 peer-reviewed papers (H-index of 34).