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BuchKartoniert, Paperback
443 Seiten
Englisch
Springererschienen am05.03.20242023
Data from case control, epigenetic and mendelian randomization studies indicate that people with elevated Lp(a) have a two-fold to four-fold increased risk of cardiovascular events compared to people with low Lp(a) levels.mehr
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EUR235,39
BuchKartoniert, Paperback
EUR165,84

Produkt

KlappentextData from case control, epigenetic and mendelian randomization studies indicate that people with elevated Lp(a) have a two-fold to four-fold increased risk of cardiovascular events compared to people with low Lp(a) levels.
Details
ISBN/GTIN978-3-031-24577-0
ProduktartBuch
EinbandartKartoniert, Paperback
Verlag
Erscheinungsjahr2024
Erscheinungsdatum05.03.2024
Auflage2023
ReiheContemporary Cardiology
Seiten443 Seiten
SpracheEnglisch
IllustrationenXVII, 443 p. 92 illus., 76 illus. in color.
Artikel-Nr.55888915
Rubriken
GenreMedizin

Inhalt/Kritik

Inhaltsverzeichnis
60 years of Lp(a) research-From Ouchterlonys double diffusion to a significant risk factor for CHD.- Lp(a) structure and composition.- Genetics of Lipoprotein(a).- Lp(a) metabolism.- Contemporary aspects of Lp(a) metabolism and therapies based on tracer kinetic methods.- Role of Proprotein Convertase Subtilisin Kexin type 9 in Lipoprotein(a) Metabolism.- The Role of Cell Surface Receptors in Lp(a) Metabolism.- Physiological Roles And Functions Of Lipoprotein(a).- The role of Lp(a) in Atherosclerosis: An overview.- Role of macrophages in Lp(a) pathophysiology.- Thrombosis, Inflammation and Lipoprotein(a): Clinical Implications .- The role of the kidney in Lp(a) physiology and pathophysiology.- Lp(a) as a cardiovascular risk factor.- Lp(a) and aortic valve stenosis, stroke, and other non-coronary cardiovascular diseases.- Lp(a) in cardiovascular disease: Evidence from Large Epidemiological Studies.- Lipoprotein(A) And Immunity.- When to measure Lp(a) .- Measurement of Lipoprotein (a) in the Clinical Laboratory.- Standardization of analytical methods for the measurement of Lipoprotein(a): bridging  past and future initiatives.- Establishing an SI-traceable Reference Measurement System for Lp(a), based on Quantitative Protein Mass Spectrometry and Molar Units.- Compounds that impact Lp(a) concentrations.- Antisense oligonucleotide therapy to treat elevated lipoprotein(a).- Lipoprotein apheresis for reduction of Lipoprotein(a).- Elevated Lp(a) - Why Should I Test For It, If I Cannot Treat It? A Patient´s Perspective .- Burning unanswered questions Therapy.mehr

Autor

Karam Kostner, MD, Ph.D., FRACP, FCSANZ
Associate Professor of Medicine


University of Queensland and Mater Hospital
Brisbane, Australia




Gerhard M. Kostner, Ph.D.
Emeritus Professor of Biochemistry and Molecular Biology


Medical University of Graz, Austria
Graz, Austria



Peter P. Toth, M.D. , PhD, FAHA, FESC, FACC

Adjunct Professor of Medicine

Division of Cardiology

Johns Hopkins University School of Medicine

Baltimore, Maryland USA
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