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Induced Pluripotent Stem Cells in Brain Diseases

Understanding the Methods, Epigenetic Basis, and Applications for Regenerative Medicine.
BuchKartoniert, Paperback
Englisch
Springer Netherlandserschienen am24.11.20112012
This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson´s disease and Vanishing White Matter (VWM).âmehr
Verfügbare Formate
BuchKartoniert, Paperback
EUR53,49
E-BookPDF1 - PDF WatermarkE-Book
EUR53,49

Produkt

KlappentextThis book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson´s disease and Vanishing White Matter (VWM).â
Details
ISBN/GTIN978-94-007-2815-8
ProduktartBuch
EinbandartKartoniert, Paperback
Erscheinungsjahr2011
Erscheinungsdatum24.11.2011
Auflage2012
SpracheEnglisch
MasseBreite 155 mm, Höhe 235 mm, Dicke 5 mm
Gewicht131 g
Artikel-Nr.11686121

Inhalt/Kritik

Inhaltsverzeichnis
I. Introduction.- II. Cell Reprogramming: A New Era in Regenerative Medicine.- a. Stem Cells.- b. Reprogramming Methods.- c. Measuring Pluripotency, Efficiency, and Identity.- d. Induced Pluripotent Stem Cells versus Embryonic Stem Cells.- III. Understanding Epigenetic Memory is the Key to Successful Reprogramming.- a. Pre-fertilization to Embryo.- b. Epigenetic Control in De-, Re-, and Trans-differentiation.- IV. Prospects for Cell Replacement Therapies for Brain Diseases.- a. Parkinson´s Disease.- b. Childhood Brain White Matter Disorders.- V. Conclusions.- VI. Acknowledgement.- VII. References.mehr

Autor

Dr. Vivi M. Heine is an assistant professor in the Department of Pediatrics of the VU University Medical Center in Amsterdam, Netherlands. Dr. Heine earned her doctoral degree in Neurobiology from the University of Amsterdam, Netherlands. She then received post-doctoral training at the Dana Farber Cancer Institute, Harvard University, Boston and at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California at San Francisco. She obtained a tenure track position in 2010.