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Targets of Cancer Diagnosis and Treatment

E-BookPDF1 - PDF WatermarkE-Book
Englisch
Springer International Publishingerschienen am05.05.20221st ed. 2022
This third and final volume in the 'Ion Transport in Tumor Biology' collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. 

As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application.
As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.
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Verfügbare Formate
BuchGebunden
EUR149,79
E-BookPDF1 - PDF WatermarkE-Book
EUR139,09

Produkt

KlappentextThis third and final volume in the 'Ion Transport in Tumor Biology' collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. 

As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application.
As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.
Details
Weitere ISBN/GTIN9783031039942
ProduktartE-Book
EinbandartE-Book
FormatPDF
Format Hinweis1 - PDF Watermark
FormatE107
Erscheinungsjahr2022
Erscheinungsdatum05.05.2022
Auflage1st ed. 2022
Reihen-Nr.183
SpracheEnglisch
IllustrationenX, 277 p. 30 illus., 20 illus. in color.
Artikel-Nr.9010239
Rubriken
Genre9200

Inhalt/Kritik

Inhaltsverzeichnis
Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges.- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer.- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk.- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics.- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research.- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions.- Ion Transport and Radioresistance.- Ion Transporting Proteins and Cancer: Progress and Perspectives.mehr